Results 61 to 70 of about 10,569 (220)
Advanced Science, Volume 13, Issue 4, 19 January 2026.An Allosteric Strategy for Thyroid Eye Disease This illustration depicts an aptamer (purple) binding to the target protein (white) at an allosteric site. This strategic binding induces a conformational change that acts as a shield, preventing pathogenic autoantibodies (red) from initiating the disease cascade, while leaving the protein's normal ...
Yanchen Zhang +16 more
wiley +1 more source
Application of machine learning in the diagnostic work‐up of telomere biology disorders
HemaSphere, Volume 10, Issue 1, January 2026.ABSTRACT We applied supervised and unsupervised machine learning (ML) analyses to a cohort of 140 patients referred to the Hematology Unit of the G. Gaslini Institute from 1989 to 2023 for persistent cytopenia and/or features suggestive of telomere biology disorders (TBDs). Patients were labeled as “TBD” (n = 20, established molecular diagnosis of TBD),
Erika Massaccesi +28 more
wiley +1 more source
Endoscopic orbital decompression in Graves ophthalmopathy - Case report
, 2018 Graves ophthalmopathy, an autoimmune disease, associated with hypermetabolism, enlargement of the thyroid gland and exophthalmia are the most frequent expressions of Graves’ disease, which often require surgical treatment.
Tatiana Decuseara +5 more
core +1 more source
A Pruritic Predicament: An Unusual Presentation of Graves’ Disease Complicated by Pregnancy
Case Reports in Medicine, Volume 2026, Issue 1, 2026.Pruritus is a known but uncommon symptom of hyperthyroidism that can be misinterpreted or overlooked in a patient presentation. This is a case report of a 40‐year‐old female who presents with a 3‐month history of severe, worsening pruritus. Further history demonstrated potential signs of hyperthyroidism, and laboratory values demonstrated low TSH ...
Rob Lawless +4 more
wiley +1 more source
The relationship between Graves’ ophthalmopathy and dry eye syndrome
, 2014 Jessica H Selter,1 Anisa I Gire,2 Shameema Sikder2 1Johns Hopkins School of Medicine, 2Wilmer Ophthalmological Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA Background: A complex relationship between Graves&rsquo ...
Sikder S, Selter JH, Gire AI
core
Postural variation of exophthalmometry in Graves′ ophthalmopathy
Indian Journal of Ophthalmology, 1990 30 patients with Graves′ ophthalmopathy were subjected to exophthalmometry in the upright and supine positions to determine if the difference in exophthalmometer readings in these two situations are significantly different and would help in ...
Asad Rajvardhan +3 more
doaj
Exploring Thyrotoxic Hypercalcaemia Through Two Cases: A Myriad of Uncertainties
Case Reports in Endocrinology, Volume 2026, Issue 1, 2026.Hypercalcaemia is a recognised complication of thyrotoxicosis usually related to increased bone resorption. However, coexistent hyperphosphataemia is uncommon and may create diagnostic uncertainty. It is postulated that serum calcium and phosphate levels rise due to high bone turnover and increased renal reabsorption of phosphate in response to excess ...
Don Asiri Abeysiriwardana +4 more
wiley +1 more source
Graves' ophthalmopathy: natural history and treatment outcomes
, 2001 The pathogenesis of Graves' ophthalmopathy has not been yet clarified, and from a therapeutic standpoint Graves' ophthalmopathy remains an enigma.
Bürgi, U +4 more
core
Evaluation of clinical features and risk factors in juvenile Graves' ophthalmopathy [PDF]
, 2016 [...]. Aim and objectives. The aim of the present study was to evaluate the features of juvenile Graves' ophthalmopathy and identify the risk factors that may influence the development of the disease. The objectives of the study were as follows: 1.
Jarušaitienė, Dalia
core
The Influence of Prior Hyperthyroidism on Euthyroid Graves’ Ophthalmopathy [PDF]
, 2014 Background. To investigate the influence of previous exposure to elevated thyroid hormones in euthyroid Graves' ophthalmopathy. Design. Retrospective, observational case series in university setting Median follow-up of 1 year with ranges of 0,8-7,6 years.
Ilse Mombaerts +5 more
core +1 more source