Results 91 to 100 of about 43,064 (280)

SUSCEPTIBILITY OF Listeria monocytogenes STRAINS ISOLATED FROM FOOD TO ANTIMICROBIAL AGENTS

open access: yesItalian Journal of Food Safety, 2013
The objective of this study was to evaluate the susceptibility of 40 L. monocytogenes strains isolated from seafood and processing environments to 19 antibiotics currently used in veterinary and human therapy.
E. Zanardi   +5 more
doaj   +1 more source

The antimicrobial susceptibility in adult invasive pneumococcal disease in the era of pneumococcus vaccination: A hospital-based observational study in Taiwan

open access: yesJournal of Microbiology, Immunology and Infection, 2020
Background: A regional antibiotic susceptibility data of common pathogens is crucial to first-line physician for clinical judgment and appropriate selection of antimicrobial agents.
Meng-Chien Lee   +6 more
doaj   +1 more source

The impact of revised CLSI cefazolin breakpoints on the clinical outcomes of Escherichia coli bacteremia

open access: yesJournal of Microbiology, Immunology and Infection, 2016
The susceptibility breakpoints of cephalosporins for Enterobacteriaceae were revised by the Clinical and Laboratory Standards Institute (CLSI) in 2010 and 2011. The clinical outcome and susceptibility data were analyzed to evaluate the impact of revised CLSI cefazolin breakpoints on the treatment of Escherichia coli bacteremia.Forty-three bacteremic ...
Wang, Kung-Ching   +3 more
openaire   +2 more sources

Validated, Reliable, and Novel Skin Frailty Scale for Outpatient Usage and Its Association With Age, Sex, and Non‐Melanoma Skin Cancer: An Observational Study

open access: yesJEADV Clinical Practice, EarlyView.
Skin frailty (SF) is a common condition affecting adults aged ≥65 years. However, the lack of a validated and reliable visual scale to assess SF severity is a barrier to clinical care and research. In this study, we developed a 9‐parameter Skin Frailty Score (SFS), validated by two board‐certified dermatologists and meeting item and scale level content
Po‐Han Ho   +9 more
wiley   +1 more source

Kidney Function Trajectories With Mechanical Circulatory Support

open access: yesKidney International Reports
Introduction: Adverse long-term kidney outcomes with left ventricular assist devices (LVADs) are common but little understood. Creatinine-based estimated glomerular filtration rate (eGFR) is used clinically in this setting; however, it is of uncertain ...
Carl P. Walther   +6 more
doaj   +1 more source

Oncogenic KRAS Rewires Stress Granule Dynamics: Mechanisms and Therapeutic Opportunities

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Stress granules (SGs) are dynamic, membrane‐less structures that form in response to various cellular stresses, including metabolic, oxidative, and therapeutic challenges. They function as adaptive hubs and reorganize protein synthesis and signaling networks to help cells survive under stress. In cancer, these condensates are often hijacked to
Msimisi Ndzinisa   +2 more
wiley   +1 more source

Breakpoint-specific multiplex polymerase chain reaction allows the detection of IKZF1 intragenic deletions and minimal residual disease monitoring in B-cell precursor acute lymphoblastic leukemia

open access: yesHaematologica, 2013
Deletion of the Ikaros (IKZF1) gene is an oncogenic lesion frequently associated with BCR-ABL1-positive acute lymphoblastic leukemias. It is also found in a fraction of BCR-ABL1-negative B-cell precursor acute lymphoblastic leukemias, and early studies ...
Aurélie Caye   +9 more
doaj   +1 more source

Chronic, Environmentally Relevant PM2.5 Exposure Exacerbates Metabolic Dysfunction‐Associated Steatotic Liver Disease and Early‐Stage Renal Dysfunction in a Rodent Model

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT While epidemiological studies link fine particulate matter (PM2.5) exposure to metabolic dysfunction‐associated steatotic liver disease (MASLD) and renal dysfunction, a translational gap exists, as most animal models utilize acute, high‐dose exposures that poorly reflect chronic, moderate‐level human scenarios.
Yi‐Siao Chen   +11 more
wiley   +1 more source

Assessment of long-read strategies for the enrichment of clinically relevant breakpoints in lymphomas: towards a diagnostic implementation

open access: yesAnnals of Hematology
Recurrent chromosomal translocations are hallmarks of many hematological malignancies, including lymphomas and leukemias. Accurate breakpoint detection is essential for diagnostics, treatment optimization, and disease monitoring.
Filip Pardy   +6 more
doaj   +1 more source

Isolated trisomy 7q21.2-31.31 resulting from a complex familial rearrangement involving chromosomes 7, 9 and 10

open access: yesMolecular Cytogenetics, 2011
Background Genotype-phenotype correlations for chromosomal imbalances are often limited by overlapping effects of partial trisomy and monosomy resulting from unbalanced translocations and by poor resolution of banding analysis for breakpoint designation.
Weimer Jörg   +6 more
doaj   +1 more source

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