Results 101 to 110 of about 43,064 (280)

Mycobacterium tuberculosis pncA polymorphisms that do not confer pyrazinamide resistance at a breakpoint concentration of 100 micrograms per milliliter in MGIT [PDF]

, 2015
CITATION: Whitfield, M. G. et al. 2015. Mycobacterium tuberculosis pncA polymorphisms that do not confer pyrazinamide resistance at a breakpoint concentration of 100 micrograms per milliliter in MGIT.
Birkness, Kris, Morlock, Glenn, Morlock, Glenm, Willby, Melisa, Whitfield, Michael G., Posey, James E., Mercante, Alexandra, Hughes, Kelsey, Van Rie, Annelies, Streicher, Elizabeth M., Sampson, Samantha L., Sirgel, Frik A., Van Helden, Paul D., Warren, Robin M.   +13 more
core   +1 more source

Optical mapping reveals a higher level of large‐scale structural variants in a family with paternally transmitted myotonic dystrophy and independent Parkinson's disease

The Journal of Pathology, EarlyView.
Abstract Myotonic dystrophy type 1 (DM1) is a clinically challenging multisystem neuromuscular hereditary disorder, with generational increase in severity and earlier age at onset. It is caused by an unstable cytosine‐thymine‐guanine repeat expansion at the DMPK locus, accompanied by associated genetic and epigenetic modifications.
Md Mehedi Hasan, Jenna Craddock, Tingting Gong, Ruth J Lyons, Igor Stevanovski, Sanjog R Chintalaphani, Ira W Deveson, Weerachai Jaratlerdsiri, Kishore R Kumar, Vanessa M Hayes   +9 more
wiley   +1 more source

Canadian impact of CLSI aminoglycoside breakpoint changes for selected gram-negative bacteria

Antimicrobial Stewardship & Healthcare Epidemiology
We evaluated the impact of recent revisions to the Clinical and Laboratory Standards Institute (CLSI) aminoglycoside breakpoints on susceptibility within Enterobacterales and Pseudomonas aeruginosa at a Canadian academic hospital.
Ellen Germaine Avery, Taylor Laughlin, Kevin Brown, Larissa M. Matukas, Elizabeth Leung   +4 more
doaj   +1 more source

Antifungal Breakpoints of Non-albicans Candida Clinical Isolates in Vitek-2 Compact

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2015
Sir, The incidence and diversity of infections caused by non-albicans Candida species (NAC) have shown a substantial increase in recent years. Given the growing number of susceptible patients with compromised immunity as a consequence of HIV infection, cancer chemotherapy and transplantation associated immunosuppression, NAC has emerged as an ...
Arunava Kali, Kunigal Srinivasaiah Seetha, Sreenivasan Srirangaraj   +2 more
openaire   +3 more sources

Heterozygous Beta‐Thalassaemia in Pregnancy: Two Rare Causes of Severe Fetal Anemia Requiring Intrauterine Blood Transfusions

Prenatal Diagnosis, EarlyView.
ABSTRACT Aim In this article, we present two cases of severe fetal hemolytic anemia based on a beta‐thalassaemia trait inherited from a single parent. Results These cases, presented at 20 and 28 weeks' gestation, necessitated intra‐uterine blood transfusions.
Eva van der Meij, Frans J. W. Smiers, Tamara T. Koopmann, Ingrid Krapels, Kaatje LePoole, Enrico Lopriore, Johanna M. Middeldorp, Claudia S. Ootjers, Volkher Scharnhorst, Hubertina C. J. Scheepers, Cornelis L. Harteveld, E. J. T. (Joanne) Verweij   +11 more
wiley   +1 more source

Amphetamine increases motivation of humans and mice as measured by breakpoint, but does not affect an Electroencephalographic biomarker [PDF]

Translation of drug targets from preclinical studies to clinical trials has been aided by cross-species behavioral tasks, but evidence for brain-based engagement during task performance is still required. Cross-species progressive ratio breakpoint tasks (
Bhakta, Savita G, Cavanagh, James F, Noback, Michael, Kotz, Juliana E, Talledo, Jo A, Benster, Lindsay, Swerdlow, Neal R, Nungaray, John A, Light, Gregory A, Brigman, Jonathan L, Young, Jared W, Roberts, Benjamin Z   +11 more
core   +1 more source

Illegal Gold Mining in the Brazilian Amazon: Environmental Degradation in Yanomami Indigenous Lands, and Regulatory Failures

Sustainable Development, EarlyView.
ABSTRACT Illegal gold mining has emerged as a major sustainability threat in the Amazon, eroding Indigenous rights, forest integrity, and climate mitigation efforts. This study examines how international market incentives relate to the expansion of illegal mining and associated deforestation within the Yanomami Indigenous Territory (YIT) from 2008 to ...
Shirléia Lago Santos, Ana Claudia de Araujo Moxotó, Jurandir Moura Dutra   +2 more
wiley   +1 more source

Relation between Genomic DNA Breakpoints in MLL Gene and Treatment Outcome in Infants with Acute Leukemia

Клиническая онкогематология, 2016
Aim. To evaluate the relation between genomic DNA breakpoints in MLL and translocation partner genes (TPG) and clinical parameters of infant AL. Methods.
Grigorii Anatol’evich Tsaur, C. Meyer, T. O. Riger, A. M. Kustanovich, E. V. Fleischman, Yu. V. Ol’shanskaya, A. M. Popov, O. I. Sokova, E. A. Matveeva, O. V. Nikulina, A. E. Drui, O. R. Arakaev, O. V. Streneva, S. A. Rumyantsev, E. V. Shorikov, A. G. Solodovnikov, L. I. Savel’ev, R. Marschalek, L. G. Fechina   +18 more
doaj   +1 more source

Isolation of carbapenem‐resistant Pseudomonas aeruginosa and other Gram‐negative ESKAPE organisms from samples of raw‐meat diets for dogs in the UK

Veterinary Record, EarlyView.
Abstract Background Gram‐negative ESKAPE organisms are an emerging threat in veterinary medicine that also have zoonotic potential. However, little is known about the prevalence and risks of these organisms in pet food. We present the incidental finding of gram‐negative ESKAPE organisms within samples of raw meat diets for dogs in the United Kingdom ...
Genever Morgan, Nicola Williams, Jenny Llewelyn, Sam Haldenby, Gina Pinchbeck, Dorina Timofte   +5 more
wiley   +1 more source

Genomic breakpoints and clinical features of MLL-TET1 rearrangement in acute leukemias

Haematologica, 2012
Recent rapid developments in new technology such as whole genome/exome sequencing have revealed that novel mutations in genes such as DNMT3A , IDH1 , IDH2 and TET2 contribute to the main process of leukemogenesis in patients with normal karyotype acute myeloid leukemia (AML).[1][1] Among these ...
Sang-Guk Lee, Sun Young Cho, Min Jin Kim, Seung Hwan Oh, Eun Hae Cho, Sanggyu Lee, Eun Jung Baek, Jung Hye Choi, Stefan K. Bohlander, Laurence Lode, Steven Richebourg, Hwi-Joong Yoon, Rolf Marschalek, Claus Meyer, Tae Sung Park   +14 more
openaire   +3 more sources