Results 101 to 110 of about 68,369 (257)

Quantile calculus and censored regression

, 2010
Quantile regression has been advocated in survival analysis to assess evolving covariate effects. However, challenges arise when the censoring time is not always observed and may be covariate-dependent, particularly in the presence of continuously ...
Huang, Yijian
core   +1 more source

Dynamics of natural killer cell function upon recurrent stimulation

Biotechnology Progress, EarlyView.
Weekly stimulation of peripheral blood‐derived NK cells with engineered K562 feeder cells resulted in two distinct growth phases, shifting around Day 21–26. Cells in growth phase 2 exhibited slower growth, reduced metabolic activity, and lower cytotoxicity than cells from growth phase 1, which has implications for NK cell biomanufacturing.
Jennifer One, Janani Narayan, Frank Cichocki, Wei‐Shou Hu, Samira M. Azarin   +4 more
wiley   +1 more source

Genomic catastrophes frequently arise in esophageal adenocarcinoma and drive tumorigenesis [PDF]

, 2014
Oesophageal adenocarcinoma (EAC) incidence is rapidly increasing in Western countries. A better understanding of EAC underpins efforts to improve early detection and treatment outcomes.
Anderson, M, Bailey, P, Barbour, A, Bruxner, T, Campbell, P, Christ, A, Fink, J, Gotley, D, Grimmond, S, Harliwong, I, Hayward, N, Holmes, O, Hussey, D, Idrisoglu, S, Kazakoff, S, Krause, L, Lampe, G, Leonard, C, Loffler, K, Lord, R, Manning, S, Miller, D, Nancarrow, D, Newell, F, Nones, K, Nourbakhsh, E, Nourse, C, Patch, A, Pearson, J, Phillips, W, Quek, K, Quinn, M, Reid, L, Simpson, P, Smithers, B, Tang, Y, Waddell, N, Waddell, N, Watson, D, Wayte, N, Whiteman, D, Wilson, P, Wood, S, Xu, Q   +43 more
core   +4 more sources

Challenges and Pitfalls to Diagnosing NUTM1‐Rearranged Neoplasia of the Pancreas by Cytology and Ancillary Studies

Diagnostic Cytopathology, EarlyView.
ABSTRACT Fine‐needle aspiration cytology specimens are frequently utilized for ancillary studies to identify diagnostic and prognostic information. This case highlights diagnostic pitfalls and challenges in diagnosing NUTM1‐rearranged neoplasia on pancreatic cytology.
Terrance J. Lynn
wiley   +1 more source

Genetic characterization of human coxsackievirus A6 variants associated with atypical hand, foot and mouth disease: a potential role of recombination in emergence and pathogenicity [PDF]

, 2015
Human coxsackievirus A6 (CVA6) is an enterically transmitted enterovirus. Until recently, CVA6 infections were considered as being of minor clinical significance, and only rarely aetiologically linked with hand, foot and mouth disease (HFMD) associated ...
Gaunt, E, Harvala, H, Simmonds, P, Sreenu, VB, Thomson, E, Waris, M, Österback, R   +6 more
core   +1 more source

Genomic breakpoints and clinical features of MLL-TET1 rearrangement in acute leukemias

Haematologica, 2012
Recent rapid developments in new technology such as whole genome/exome sequencing have revealed that novel mutations in genes such as DNMT3A , IDH1 , IDH2 and TET2 contribute to the main process of leukemogenesis in patients with normal karyotype acute myeloid leukemia (AML).[1][1] Among these ...
Sang-Guk Lee, Sun Young Cho, Min Jin Kim, Seung Hwan Oh, Eun Hae Cho, Sanggyu Lee, Eun Jung Baek, Jung Hye Choi, Stefan K. Bohlander, Laurence Lode, Steven Richebourg, Hwi-Joong Yoon, Rolf Marschalek, Claus Meyer, Tae Sung Park   +14 more
openaire   +3 more sources

Pathogenesis and potential therapeutic targets of trichorhinophalangeal syndrome; lessons obtained from animal studies

Developmental Dynamics, EarlyView.
Abstract Trichorhinophalangeal syndrome (TRPS) is a rare genetic disease inherited in an autosomal dominant manner. It occurs in 1 in 100,000 people globally and is caused by several types of mutations of the TRPS1 gene. Since the first human patient was reported in 1966, typical and atypical pathologies, disease courses, and treatment case ...
Naoya Saeki, Rinna Kanai, Sayuri Tatsuta, Shinichi Kawaguchi, Masatsune Itoh, Shinsuke Ohba, Makoto Abe   +6 more
wiley   +1 more source

SUSCEPTIBILITY OF Listeria monocytogenes STRAINS ISOLATED FROM FOOD TO ANTIMICROBIAL AGENTS

Italian Journal of Food Safety, 2013
The objective of this study was to evaluate the susceptibility of 40 L. monocytogenes strains isolated from seafood and processing environments to 19 antibiotics currently used in veterinary and human therapy.
E. Zanardi, S. Ghidini, A. Ianieri, M. Conter, A. Mureddu, D. Paludi   +5 more
doaj   +1 more source

The antimicrobial susceptibility in adult invasive pneumococcal disease in the era of pneumococcus vaccination: A hospital-based observational study in Taiwan

Journal of Microbiology, Immunology and Infection, 2020
Background: A regional antibiotic susceptibility data of common pathogens is crucial to first-line physician for clinical judgment and appropriate selection of antimicrobial agents.
Meng-Chien Lee, Kuang-Che Kuo, Chen-Hsiang Lee, Yu-Chia Hsieh, Ming-Han Tsai, Ching-Tai Huang, Yhu-Chering Huang   +6 more
doaj   +1 more source

Antimicrobial Susceptibility Patterns in Urinary Tract Infections in Dogs (2010-2013). [PDF]

, 2015
BackgroundUrinary tract infections (UTIs) are common in dogs. The responsible bacterial populations have evolved with increasing resistance to many antimicrobials.ObjectiveTo characterize the antimicrobial susceptibility patterns of canine urinary tract ...
Epstein, SE, Westropp, JL, Wong, C
core   +1 more source