Results 81 to 90 of about 7,450,889 (232)

Follow-up for breast cancer - the patients' view [PDF]

, 2006
Background: International and national guidelines (S3 guideline) for the surveillance of post-treatment breast cancer patients recommend a clinical follow-up including routine history and physical examination and regular mammograms.
Bauerfeind, Ingo, Ingo Bauerfeind, Margrit Glattes, Dorit Lässig, Laessig, Dorit, Beckmann, Matthias W., Petra Stieber, Stemmler, Hans-Joachim, Heinemann, Volker, Hans-Joachim Stemmler, Matthias Beckmann, Stieber, Petra, Volker Heinemann, Verena Hoffmann, Fasching, Peter, Hoffmann, Verena, Peter Fasching, Glattes, Margrit, Ursula Goldmann-Posch, Goldmann-Posch, Ursula   +19 more
core   +1 more source

Clinicopathological profile and treatment outcomes of bilateral breast cancer: A study from tertiary cancer center in South India

Indian Journal of Medical and Paediatric Oncology, 2018
Background: Bilateral breast cancer (BBC) is a rare clinical entity with limited data regarding clinicopathological aspects and treatment guidelines. Materials and Methods: This was an observational study of patients diagnosed with BBC from August 2012 ...
Linu Abraham Jacob, Abhishek Anand, Kuntegowdanahalli C Lakshmaiah, Govind K Babu, Dasappa Lokanatha, M C Suresh Babu, Kadabur N Lokesh, Antapura Haleshappa Rudresha, L K Rajeev, Deepak Koppaka   +9 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

HSE Post Mortem Examination Service Process Map (2023)

, 2023
The purpose of the HSE Post Mortem Examination Service Process Map (2023) is to share a process map for the delivery of PME Services based on current legal requirements, professional standards and international best practice.
HSE Guidelines for Post Mortem Examination Services: Review Group
core  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Health Beliefs about Mammography and Clinical Breast Examination among Female Healthcare Providers in Tabriz Health Centers

نشریه پرستاری ایران, 2011
Background & Aim: Mammography and clinical breast examination have been recommended for early detection of breast cancer in asymptomatic women. Health beliefs play an important role in people’s tendency toward participation in health promotion behaviors.
Mokhtari L. MSc, Baradaran Rezaee M. MSc, Mohammadpour Asl A. MSc, Mousavi SM PhD   +3 more
doaj  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Breast Cancer Prevention and Management: A Primer for General Practitioners

Preventive Medicine: Research & Reviews
Breast cancer is the most common malignancy among women in India and a significant contributor to cancer-related mortality. Early detection and evidence-based clinical interventions can substantially reduce the burden of breast cancer-related morbidity ...
Neha Singh, Khushboo Bhange, Kamlesh K Jain, Kanika Arora, Jitendra K. Meena   +4 more
doaj   +1 more source

The Clinical Breast Examination: A Useful Screening Tool?

Journal of Patient-Centered Research and Reviews, 2015
The standardization of the clinical breast examination as a screening tool for breast cancer has been a topic of controversy. Current recommendations vary significantly from organization to organization without consensus. There currently does not seem to
Jennifer Lo
doaj   +1 more source