Results 91 to 100 of about 8,108,152 (305)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Department of Chemistry Newsletter (1986, No. 9)

, 1986
The newsletter of the Department of Chemistry, published once or twice a year, highlights people, events, and facilities. Content includes brief articles on new faculty hires, faculty and staff retirements, obituaries, major facilities and equipment ...
Department of Chemistry
core   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Department of Chemistry Newsletter (1988, No. 11)

, 1988
The newsletter of the Department of Chemistry, published once or twice a year, highlights people, events, and facilities. Content includes brief articles on new faculty hires, faculty and staff retirements, obituaries, major facilities and equipment ...
Department of Chemistry
core   +1 more source

Clinical Reasoning as the Guiding Framework in Medical Biochemical Test Reporting

Diagnostics
Clinical biochemical reports should reflect the clinical perspective, be well organized and biologically oriented, and present accurate reference values based on clinically relevant distributions.
Torleif Trydal, Geir Erland Tjønnfjord
doaj   +1 more source

Analytical comparison of the portable ENNOLIFE HCA-TC-200 analyser and the Beckman UniCel DXC 880I for hepatorenal and urinary biomarkers: Implications for future point-of-care use [PDF]

Journal of Medical Biochemistry
Background: Accurate and efficient chemical analysers play a critical role in modern healthcare, particularly in community medicine, where early diagnosis and intervention can significantly improve patient outcomes.
Lai Yung-Han, Zheng Cai-Mei, Lin Hsin-Ting, Wang Pei-Yu, Yang Chi-Chen, Fang Yu-Ann, Chang Tian-Jong, Lin Chia-Wei, Lin Yen-Kuang, Lin Yuh-Feng, Chen Ming-Yao, Tsai Hsiao-Chung, Chiang Huai-Chih, Hu Pin-Jen   +13 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Synthesis, structure and pyrolysis of stabilised phosphonium ylides containing saturated oxygen heterocycles [PDF]

, 2016
A range of twelve stabilised phosphonium ylides containing tetrahydrofuran, tetrahydropyran or 2,2-dimethyl-1,3-dioxolane rings have been prepared and fully characterised, including one X-ray structure determination of each type.
Sahabo, Nina Carole, Rouxel, C., McCarron, Hollie B, Slawin, Alexandra Martha Zoya, Aitken, Robert Alan, Karodia, Nazira, McCarron, H.B., Rouxel, Cécile, Aitken, R.A., Slawin, A.M.Z., Sahabo, Nina   +10 more
core   +1 more source

Suspected Permethrin-Containing Powder Bath Poisoning in a Flock of Mountain Quail (Oreortyx pictus)

Animals
Generally, birds are less sensitive to pyrethrins and pyrethroids compared to mammals; however, suspected permethrin toxicosis was fatal in seven mountain quails (Oreortyx pictus) treated with a permethrin-containing powder bath.
János Gál, Miklós Marosán, Míra Mándoki, Lilla Dénes, Miklós Süth, Dániel Pleva, József Lehel   +6 more
doaj   +1 more source