Results 61 to 70 of about 1,123,091 (301)

Colloidal Assemblies of Oriented Maghemite Nanocrystals and their NMR Relaxometric Properties

open access: yes, 2014
Elevated-temperature polyol-based colloidal-chemistry approach allows for the development of size-tunable (50 and 86 nm) assemblies of maghemite iso-oriented nanocrystals, with enhanced magnetization.
Bordonali, L.   +9 more
core   +1 more source

Plasma N-Terminal Pro-Brain Natriuretic Peptide as Prognostic Marker in Fatal Cardial Decompensation with Sunitinib Malate Therapy [PDF]

open access: yes, 2010
A 74-year-old man with metastatic renal cell carcinoma and a history of cardiac failure was treated with sunitinib malate. MUGA echocardiography could not detect a relevant change in the ejection fraction although the clinical situation of the patient ...
Haseke, Nicolas   +4 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Clinical Chemistry and Autoverification: A Path Less Traversed [PDF]

open access: yesIndian Journal of Medical Biochemistry
Aims and background: Autoverification (AV) is an application of artificial intelligence that uses computer-based algorithmically established rules for release of patient reports. This allows effective time management, prevents probable laboratory errors,
Rashmi Rasi Datta, Anurag Bansal
doaj   +1 more source

Efficacy and safety of the long-term oral administration of carprofen in the treatment of osteoarthritis in dogs [PDF]

open access: yes, 2007
The aim of this study conducted in France was to confirm the efficacy and safety of the oral administration of carprofen (Rimadyl®) at 4 mg/kg once a day during four months in the treatment of clinically chronic osteoarthritis in dogs.
Autefage, André, Gosselin, Jacques
core  

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

The schemes of external quality control in laboratory medicine in the Balkans [PDF]

open access: yesJournal of Medical Biochemistry, 2007
There are many differences between the national External Quality Control Schemes all around Europe, but the most important ones are certainly those between the countries of the Balkan region.
Karkalousos Petros
doaj  

Porous Bead-Based Diagnostic Platforms: Bridging the Gaps in Healthcare

open access: yesSensors, 2012
Advances in lab-on-a-chip systems have strong potential for multiplexed detection of a wide range of analytes with reduced sample and reagent volume; lower costs and shorter analysis times.
John McDevitt   +5 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Retrospective analysis of clinical laboratory parameters in Han Wistar rat controls

open access: yesFrontiers in Toxicology
IntroductionDespite the availability of control animal data sets from toxicological studies, the influence of external factors, such as age of animals, test site and study conditions, on clinical laboratory parameters in rats is only sparsely ...
Rupert Kellner   +12 more
doaj   +1 more source

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