Results 41 to 50 of about 517,662 (262)
Measuring VLDL1 secretion in humans with an intravenous fat emulsion test
STAR Protocols, 2023 Summary: Tracer techniques to assess very-low-density lipoprotein (VLDL) secretion in humans are expensive, are time consuming, and require mathematical models to estimate VLDL kinetics. Here, we describe an alternative, time- and cost-efficient protocol
Matthäus Metz +3 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Food & Nutrition Research, 2014 Background: The role of micronutrient status for the incidence and clinical course of cutaneous leishmaniasis is not much studied. Still zinc supplementation in leishmaniasis has shown some effect on the clinical recovery, but the evidence in humans is ...
Miguel Guzman-Rivero +7 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Frontiers in Veterinary ScienceThe study assessed the kidney, liver, and spleen of adult male rabbits (n = 10/group) in relation to fumonisin B series exposure (10 and 20 mg FB1 + FB2 + FB3/kg feed) over a period of 65 days.
Omeralfaroug Ali +11 more
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Applicability of commercial clinical chemistry test kits for horse serum
BMC Research Notes, 2021 Objective Validation of a test method is critical for confirming that the test can generate accurate and precise data. Although commercial biochemical test kits exist there are no specific and validated commercial clinical chemistry test kits designed ...
Yoseph Cherinet Megerssa +2 more
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Intracellular Clinical Chemistry
Clinical Chemistry, 1972 Abstract The plasma compartment, on which almost all routine analyses in clinical chemistry are performed, occupies only a small part of the body, most of which consists of cells. For most components the intracellular and extracellular compartments have a different composition in health, and change differently in disease.
openaire +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Clinical Chemistry and Autoverification: A Path Less Traversed [PDF]
Indian Journal of Medical BiochemistryAims and background: Autoverification (AV) is an application of artificial intelligence that uses computer-based algorithmically established rules for release of patient reports. This allows effective time management, prevents probable laboratory errors,
Rashmi Rasi Datta, Anurag Bansal
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