A substrate promiscuous and regioselective O‐methyltransferase, SmOMT, is functionally and structurally characterized. A double mutant, SmOMTE152A/I306A, exhibited enhanced catalytic activity. By coupling this mutant with a mutant halide methyltransferase, AtHMTV140T, for SAM regeneration, a superior artificial fusion enzyme, AtHMTV140T‐L95‐SmOMTE152A ...
Xiran Xiong +11 more
wiley +1 more source
Online and face-to-face education are effective to improve clinical competence regarding nutritional care in early chronic kidney disease. [PDF]
Márquez-Herrera RM +7 more
europepmc +1 more source
The potential for using entrustable professional activities in assessing optometric clinical competence [PDF]
Will Holmes +2 more
openalex +1 more source
Development and Psychometric Evaluation of the Korean Version of the Cultural Competence Scale for Clinical Nurses [PDF]
Duckhee Chae, Chung-Yul Lee
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Lysosome‐targeting chimeras (LYTACs) enable degradation of extracellular and membrane proteins via lysosomal trafficking. We report a novel IGF‐II mutant (Del1–7, Y27L) that selectively engages IGF‐IIR while avoiding IGF‐IR and IR‐A. mutIGF‐II–based LYTACs enhance target internalization and degradation and support a genetically encodable, all‐protein ...
Yuan Zhao +16 more
wiley +1 more source
The relationship between self-directed learning ability and clinical competence among nursing students: a cross-sectional descriptive study. [PDF]
Badakhshan R +3 more
europepmc +1 more source
The Power of an Iterative Approach to Clinical Competence Assessment
Kimberly A. Gifford +2 more
openalex +2 more sources
Exploring Nursing Student Self-esteem and its Relationship to Clinical Competence Development: Protocol for A Multiphase Convergent Mixed Methods Study [PDF]
Jacinthe Dancot +6 more
openalex +1 more source

