Results 171 to 180 of about 1,803,951 (318)
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Evaluation of computer based clinical decision support system and risk chart for management of hypertension in primary care: randomised controlled trial [PDF]
, 2000 Alan Montgomery
openalex +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
THE APPLICATION OF EXTENSIVE FEATURE EXTRACTION AS A COST STRATEGY IN CLINICAL DECISION SUPPORT SYSTEM [PDF]
, 2019 Henry Odikwa
openalex +1 more source
Medics: Medical Decision Support System for Long-Duration Space Exploration [PDF]
The Autonomous Medical Operations (AMO) group at NASA Ames is developing a medical decision support system to enable astronauts on long-duration exploration missions to operate autonomously.
Colombano, Silvano +4 more
core +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Qualitative study on physicians' acceptance of a clinical decision support system for anemia management in patients receiving hemodialysis. [PDF]
BMC Health Serv ResYang JY, Cheng SH, Kuo RN.
europepmc +1 more source
Validation of an acute kidney injury prediction model as a clinical decision support system [PDF]
Giae Yun +8 more
openalex +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source