Results 101 to 110 of about 10,615,218 (316)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

National Clinical Programme for Rare Diseases Workshop on Clinical Research in Rare Diseases

, 2018
The National Clinical Programme was established in December 2013. It is an initiative of the HSE, in partnership with the Royal College of Physicians. A key objective of the Clinical Programme for Rare Diseases is to improve access for rare diseases ...
National Clinical Programme for Rare Diseases
core  

Cost implications of improving malaria diagnosis: findings from north-eastern Tanzania. [PDF]

, 2010
BACKGROUND: Over diagnosis of malaria contributes to improper treatment, wastage of drugs and resistance to the few available drugs. This paper attempts to estimate the rates of over diagnosis of malaria among children attending dispensaries in rural ...
L. Conteh, Tediosi, F., J. Bruce, Gesase Samwel, Daniel Chandramohan, Conteh L., Gosling R., Bruce, J., Gosling Roly, Mosha, J. F., Jacklin F. Mosha, Mosha Jacklin F., Tediosi F., Tediosi Fabrizio, Gosling, R., J.F. Mosha, Lesong Conteh, Conteh, Lesong, Samwel Gesase, R. Gosling, Gesase, Samwel, Chandramohan Daniel, Bruce J., Jane Bruce, Jacklin F Mosha, Conteh, L., Conteh Lesong, Gesase, S., Chandramohan, Daniel, Mosha, Jacklin F, D. Chandramohan, Tediosi, Fabrizio, Gosling, Roly, Chandramohan D., Mosha J. F., Fabrizio Tediosi, S. Gesase, Gesase S., Chandramohan, D., Bruce Jane, Roly Gosling, Bruce, Jane, Mosha, Jacklin F.   +42 more
core   +2 more sources

Role of arbutin in the inhibition of FBXO5 in hepatocellular carcinoma

Discover Oncology
Purpose This work investigated the effect of FBXO5 in hepatocellular carcinoma (HCC) and the mechanism of action of arbutin in its inhibition. Methods FBXO5 mRNA and protein expressions in the tumor were assessed using TCGA, ICGC and HPA databases.
Shuo Zhang, Kai Yao, Yangjing Pi, Sen Yang, Zheng Huang, Xueshan Pan, Tonggang Li   +6 more
doaj   +1 more source

Clinical and molecular characteristics, antibiotic susceptibility, risk factors and predictors of mortality in carbapenem-resistant klebsiella pneumoniae bloodstream infections in Southern Sichuan, China: a 5-year multicenter study

Frontiers in Cellular and Infection Microbiology
BackgroundThe World Health Organization (WHO) has listed carbapenem-resistant Klebsiella pneumoniae (CRKP) as one of the key pathogens that require the highest priority for containment.
Wenchao Xie, Wenchao Xie, Wenchao Xie, Zixiang Luo, Zixiang Luo, Zixiang Luo, Chenghong Gu, yanzhi Li, yanzhi Li, yanzhi Li, Jie Deng, Jie Deng, Jie Deng, Yuling Yang, Yueshuai Wei, Yueshuai Wei, Yueshuai Wei, Yuan Jiang, Yuan Jiang, Yuan Jiang, Jinbo Liu, Jinbo Liu, Jinbo Liu, Zhangrui Zeng, Zhangrui Zeng, Zhangrui Zeng   +25 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

METTL3/IGF2BP2-Mediated m6A RNA Methylation Drives Alveolar Macrophage-Dependent Neutrophil Recruitment in Cigarette Smoke-Induced COPD

Journal of Inflammation Research
Andi Lin,1,* Jian Wang,2,* Lixing Wang,3 Yaping Zhang3,4 1The Second Clinical Medical College of Fujian Medical University, Quanzhou, Fujian, 362000, People’s Republic of China; 2Department of Pathology, The Second Affiliated Hospital of ...
Lin A, Wang J, Wang L, Zhang Y
doaj  

Differential expression of immune activation markers in T cells from patients with multiple myeloma

Frontiers in Oncology
IntroductionMultiple myeloma (MM) is the second most common hematological malignancy, characterized by the abnormal proliferation of malignant plasma cells leading to the classic CRAB symptoms.
Jiaoya Lin, Xin Zhang, Yifei Zhao, Lan Luo, Hong Yuan, Ling Zhong   +5 more
doaj   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

Diagnosis, staging and treatment of patients with gestational trophoblastic disease

, 2015
This guideline is intended for all health professionals involved in the diagnosis, staging and treatment of patients with GTD, such as gynaecologists, radiologists, pathologists, surgeons, medical oncologists, GPs and nursing staff.
National Clinical Effectiveness Committee (NCEC)
core