Results 51 to 60 of about 5,202 (208)

Evaluation of Performance of Different Disease Activity Scores in Rheumatoid Arthritis Patients [PDF]

Zagazig University Medical Journal
Background: Making informed therapeutic decisions and evaluating the effectiveness of treatments depend on accurately detecting disease activity. Therefore, this study set out to evaluate the utility of various disease activity scores in a group of RA ...
Marwa Rezk, Eman Elmarghany, Hisham Habib   +2 more
doaj   +1 more source

Definition of treatment response in rheumatoid arthritis based on the simplified and the clinical disease activity index

Annals of the Rheumatic Diseases, 2012
The simplified disease activity index (SDAI) and the clinical disease activity index (CDAI) are established instruments to measure disease activity in rheumatoid arthritis (RA). To date, no validated response definitions for the SDAI and CDAI are available.The authors aimed to define minor, moderate and major response criteria for the SDAI.The authors ...
Aletaha D, Martinez-Avila J, Kvien TK, Smolen JS   +3 more
openaire   +2 more sources

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Parameters of bowel ultrasound in the assessment of IBD activity: a correlative study with clinical, endoscopic, and biomarker indices

The Egyptian Journal of Internal Medicine
Background Bowel ultrasonography (BUS) is becoming a viable, non-invasive, affordable, and radiation-free substitute for endoscopy, which is still the gold standard for evaluating Inflammatory bowel diseases activity.
May Mohsen Fawzi, Mona Ahmed Amin, Mariam Youssef Ramzy, Ahmed El Shenawy, Mahmoud Wahba   +4 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Assessment of disease activity and quality of life of Korean patients with rheumatoid arthritis

Journal of Rheumatic Diseases
The management of rheumatoid arthritis (RA) follows a treat-to-target approach, as recommended by guidelines from the American College of Rheumatology (ACR) and the European League Against Rheumatism (EULAR).
Young Ho Lee, Jae-Bum Jun
doaj   +1 more source

ELABORATION AND APPLICATION OF THE DIAGNOSTIC INDEX BASED ON MULTIVARIATE ANALYSIS OF BIOMARKERS TO DETERMINE THE ACTIVITY OF RHEUMATOID ARTHRITIS

Научно-практическая ревматология, 2014
Rheumatoid arthritis (RA) is a heterogeneous disease. The pathogenesis of this disease is based on a complex combination of genetically determined and acquired defects of the regulatory mechanisms that limit the pathological activation of the immune ...
Aleksandr A Novikov, E N Aleksandrova, E L Nasonov   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source