Results 61 to 70 of about 5,202 (208)

Clinico-epidemiological characteristics of patients with ankylosing spondylitis: experience from a specialized rheumatology centre in Bangladesh

The Egyptian Journal of Internal Medicine
Background Due to limited data on Ankylosing Spondylitis patients in Bangladesh, our cross-sectional study sought to assess the clinical characteristics and disease status of individuals with Ankylosing Spondylitis in this population.
A. F. M. Mahbubul Alam, Sajeda Islam, Md. Nazrul Islam, Minhaj Rahim Choudhury, Syed Atiqul Haq, Nadia Sultana, A. K. M. Kamruzzaman, Mohammad Abul Kalam Azad, Salwa Islam, Mohammad Jahid Hasan   +9 more
doaj   +1 more source

Correlations between ultrafast power Doppler perfusion imaging variables and clinical disease activity in rheumatoid arthritis: potential applications for diagnosing and treating patients in deep clinical remission [PDF]

Ultrasonography
Purpose This study aimed to evaluate the ability of ultrafast power Doppler (PD) to assess disease activity in rheumatoid arthritis (RA) by examining the correlations between variables from ultrafast PD perfusion imaging and clinical measures of disease ...
Kuo-Lung Lai, Pai-Chi Li
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

A comparison of 3 rheumatoid arthritis disease activity indices in routine clinical practice

Indian Journal of Rheumatology, 2017
Objective: The objective of this study was to appraise the correlation and agreement of RAPID 3 with DAS 28 and CDAI in terms of measuring disease activity/severity and for monitoring response to treatment at 2 and 4 month follow up.
Amit Kumar Das, Rathindra Nath Sarkar, Chandan Kumar Das, Ritasman Baisya, Urmimala Bhattacharjee, Pallab Biswas, Akashdip Bhattacharya   +6 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Finding the Right Index for Inflammatory Bowel Disease

Canadian Journal of Gastroenterology, 1995
Several activity indices have been developed to assess the efficacy of new therapies for inflammatory bowel disease. The ideal index should be simple to administer and quantitative.
E Jan Irvine
doaj   +1 more source

Disease Severity and Activity in Bronchiectasis: A Paradigm Shift in Bronchiectasis Management [PDF]

Tuberculosis and Respiratory Diseases
Bronchiectasis has an increasing prevalence and substantial clinical and economic burden. Therefore, physicians should identify patients with bronchiectasis at high risk of disease progression to ensure optimal management in advance. The heterogeneity of
Yunjoo Im, James D. Chalmers, Hayoung Choi   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Clinical disease activity index versus disease activity score (28 joints) for assessment of disease activity in obese patients of rheumatoid arthritis

International Journal of Advances in Medicine
Background: Measurement of disease activity by Disease Activity Score 28 joints -Erythrocyte Sedimentation Rate (DAS28-ESR), Disease Activity Score (28 joints)-C-Reactive Protein (DAS28-CRP), and Clinical Disease Activity Index (CDAI) has become an integral part of management of Rheumatoid Arthritis (RA), by ‘Treatment to Target’ approach.
Sarthak Saxena, B. K. Kundu
openaire   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source