Results 181 to 190 of about 3,432,628 (294)

Performance Trends and Grading Variability in Clinical Education: A Record-Based Cross-Sectional Study of Medical Graduate Students at Mutah University, Jordan. [PDF]

Adv Med Educ Pract
Al-Refu K, Al-Rawashdeh I, Alnawaiseh N, Sawaqed F, Al-Saraireh Y.   +4 more
europepmc   +1 more source

Dean Logan\u27s Blog: Sang Hwa Lee wins Clinical Legal Education Award [PDF]

, 2010
Roger Williams University School of Law
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Establishing Priorities for Clinical Education Research: Exploring the Views of UK Professional and Public Stakeholders. [PDF]

Clin Teach
Burford B, Yeates P, Bluemel AH, Park S, Sandars J, Henry C, Corness-Parr C, Conn R, Gale T, O'Brien T, Goddard-Fuller R, Vance G, Ellis J.   +12 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Clinical Education: Consultation-Liaison Psychology Services. [PDF]

J Clin Psychol Med Settings
Yost JS, Cavanagh CE.
europepmc   +1 more source

Outcome measures in clinical education research. [PDF]

J Clin Educ Phys Ther, 2023
Wong CK, Timmerberg JF.
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

The application of problem-based learning (PBL) guided by ChatGPT in clinical education in the Department of Nephrology. [PDF]

BMC Med Educ
Tong X, Hu Y, Long Y, Zhang Q, Yang Y, Yuan J, Zha Y.   +6 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source