Results 141 to 150 of about 8,999,736 (321)

Increased plasma proneurotensin levels identify NAFLD in adults with and without type 2 diabetes [PDF]

, 2018
Context Neurotensin (NT), an intestinal peptide released by fat ingestion, promotes lipid absorption; higher circulating NT levels are associated with type 2 diabetes (T2D), obesity, and cardiovascular disease. Whether NT is related to nonalcoholic fatty
Barchetta, Ilaria, Capoccia, Danila, Cavallo, Maria Gisella, Cimini, Flavia Agata, Di Cristofano, Claudio, Leonetti, Frida, Melander, Olle, Orho-Melander, Marju, Silecchia, Gianfranco   +8 more
core   +1 more source

Implementing physician‐led medication reviews for patients with diabetes and severe mental disorder: A randomized controlled trial

British Journal of Clinical Pharmacology, EarlyView.
Aims Patients with severe mental disorder and diabetes may be exposed to inappropriate polypharmacy increasing the risk of side effects and drug interactions. Although medication reviews may facilitate short‐term deprescribing, they are not known to affect clinical outcomes.
Johan Frederik Mebus Meyer Christensen, Signe Wegmann Düring, Gesche Jürgens   +2 more
wiley   +1 more source

A novel selective 11b-hydroxysteroid dehydrogenase type 1 inhibitor prevents human adipogenesis. [PDF]

, 2008
Glucocorticoid excess increases fat mass, preferentially within omental depots; yet circulating cortisol concentrations are normal in most patients with metabolic syndrome (MS).
Bujalska, I.J, Darimont, C, Ermolieff, J, Fanjul, A.N, Gathercole, L.L, Rejto, P.A, Stewart, P M, Tomlinson, J W   +7 more
core  

Role of imaging in the diagnosis and management of complete androgen insensitivity syndrome in adults [PDF]

, 2013
Complete androgen insensitivity syndrome is an X-linked recessive androgen receptor disorder characterized by a female phenotype with an XY karyotype.
De Visschere, Pieter, Nezzo, Marco, T'Sjoen, Guy, Villeirs, Geert, Weyers, Steven   +4 more
core   +4 more sources

DYNAMIC ENDOCRINOLOGY IN EVERYDAY CLINICAL MEDICINE* [PDF]

, 1955
Nathan B. Talbot, John D. Crawford, Gerald A. Kerrigan   +2 more
openalex   +1 more source

Appraising the visibility, relevance and impacts of clinical pharmacology

British Journal of Clinical Pharmacology, EarlyView.
Aims Clinical pharmacology (CP) used to be a strong medical and scientific field, but during the last three decades it seems to have lost some of its appeal. We reviewed the visibility, relevance and impact of CP and clinical pharmacologists across the globe and suggest ways to strengthen the discipline to address future pharmacotherapeutic challenges.
Serge Cremers, Samuel L. M. Arnold, Nilima A. Kshirsagar, Catriona Waitt, Olayinka O. Ogunleye, Lars L. Gustafsson   +5 more
wiley   +1 more source

Circulating biomarkers of kidney angiomyolipoma and cysts in tuberous sclerosis complex patients

iScience
Summary: Patients with tuberous sclerosis complex (TSC) develop multi-organ disease manifestations, with kidney angiomyolipomas (AML) and cysts being one of the most common and deadly.
Varvara I. Rubtsova, Yujin Chun, Joohwan Kim, Cuauhtemoc B. Ramirez, Sunhee Jung, Wonsuk Choi, Miranda E. Kelly, Miranda L. Lopez, Elizabeth Cassidy, Gabrielle Rushing, Dean J. Aguiar, Wei Ling Lau, Rebecca S. Ahdoot, Moyra Smith, Aimee L. Edinger, Sang-Guk Lee, Cholsoon Jang, Gina Lee   +17 more
doaj  

JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM [PDF]

, 1953
E. P. McCULLAGH
openalex   +1 more source

Alterations of appetite‐regulating hormones in risperidone treated children and adolescents—a post hoc analysis of the SPACe study

British Journal of Clinical Pharmacology, EarlyView.
Weight gain and metabolic disruptions are common in children and adolescents treated with antipsychotics, but the underlying mechanisms are unclear, complicating prevention and treatment. This study examines the impact of risperidone on appetite‐regulating hormones (insulin, leptin and bioleptin) and their relationship to body weight changes over time.
Jiayi Liang, Brenda C. M. de Winter, Rebecca A. Hermans, Sanne M. Kloosterboer, Susanne Kuckuck, Izgi Bayraktar, Liesbeth F. C. van Rossum, Manon H. J. Hillegers, Sander A. A. van den Berg, Birgit C. P. Koch, Bram Dierckx   +10 more
wiley   +1 more source

The fate of thiopurine metabolites after switching to low‐dose thiopurine with allopurinol or thioguanine in IBD patients: A retrospective analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Shunting (hypermethylating) thiopurine metabolism, characterized by excessive 6‐MMPR production and (sub)therapeutic 6‐TGN levels, poses a significant challenge in the treatment of inflammatory bowel disease (IBD). This study evaluates the metabolic outcomes of switching to low‐dose thiopurine with allopurinol (LDTA) or thioguanine (TG) in IBD ...
Ahmed B. Bayoumy, Hedwig M. A. D'Agnolo, Nanne K. H. de Boer, Chris J. J. Mulder, Luc J. J. Derijks   +4 more
wiley   +1 more source