Results 61 to 70 of about 575,974 (287)

Maternal genomic profile, gestational diabetes control, and Mediterranean diet to prevent low birth weight

open access: yesiScience
Summary: Low birth weight (LBW) is associated to poor health outcomes. Its causes include maternal lifestyle, obstetric factors, and fetal (epi)genetic abnormalities.
Ana M. Ramos-Levi   +17 more
doaj   +1 more source

Outcomes of Early Transition of Low-Risk Thyroid Cancer Patients from Specialist to Primary Care

open access: yesCurrent Oncology, 2022
Background: Recently published clinical pathways for management of thyroid cancer outlined the criteria for transitioning low-risk patients to primary care within one to five years from diagnosis. However, discharge patterns among endocrinologists remain
Patricia Nguyen   +3 more
doaj   +1 more source

CIDEC Restricts Liver Regeneration by Disturbing Lipid Droplet Triglyceride Turnover

open access: yesAdvanced Science, EarlyView.
This study identifies CIDEC, an lipid droplet (LD)‐fusion associated protein upregulated by CREBH during early regeneration, as a negative regulator of liver regeneration through its unexpected role in sequestering triglyceride (TG) within LDs. CIDEC depletion reduces LD size, mobilizes LD‐stored TG, enhances TG catabolism and free fatty acid (FFA ...
Feng Ouyang   +16 more
wiley   +1 more source

Recent progress in gene therapy for familial hypercholesterolemia treatment

open access: yesiScience
Summary: Familial hypercholesterolemia (FH) is a genetic disorder that affects 1 in 300 people, leading to high cholesterol levels and significantly increased cardiovascular risk.
Yaxin Luo   +3 more
doaj   +1 more source

Clinical signs and behavior in dogs with hypothyroidism

open access: yesMacedonian Veterinary Review, 2023
This descriptive study aims to examine the behavior of dogs diagnosed with hypothyroidism and the potential effect of hormonal treatment. Eight client-owned dogs with clinical hypothyroidism were evaluated using an adapted C-BARQ questionnaire, clinical ...
Elena Mitrevska   +3 more
doaj   +1 more source

Impact of Intended Isocaloric Early versus Late Time‐Restricted Eating on Plasma Lipidome in Women with Overweight or Obesity: Secondary Analysis of the ChronoFast Trial

open access: yesAdvanced Science, EarlyView.
Women with overweight or obesity follow intended isocaloric early and late time‐restricted eating (TRE) in a crossover trial. Shotgun plasma lipidomics reveals no significant differences between interventions, but identify pronounced lipid changes—including reductions in ceramides and phosphatidylcholines—within the early TRE.
Kristof Szekely   +15 more
wiley   +1 more source

Experiencia con el proyecto ENDMAP, una actividad formativa para médicos de familia en endocrinología y nutrición

open access: yesAtención Primaria Práctica, 2023
Resumen: Es sabido que la atención primaria (AP) en España está sometida a un importante estrés debido al gran volumen asistencial que soporta. El envejecimiento de la población, el incremento de las enfermedades crónicas, como la diabetes y los factores
Agustín Ángel Merchante Alfaro   +3 more
doaj   +1 more source

Integrating Single‐Cell Transcriptome‐Wide Mendelian Randomization and Differentially Expressed Gene Analyses to Prioritize Dynamic Immune‐Related Drug Targets for Cancers

open access: yesAdvanced Science, EarlyView.
Inspired by evidence triangulation, a new sensitivity method called MR‐DEG is developed, which uses the differentially expressed gene (DEG) results as additional evidence to minimize pleiotropic effects and strengthen Mendelian randomization (MR) causal estimates. Using dynamic single‐cell expression quantitative trait loci (eQTLs) as an example, it is
Jie Zheng   +29 more
wiley   +1 more source

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