Results 111 to 120 of about 169,755 (257)

The role of the Ethics Committees in Scientific Research in Italy: from research protocols to publication – A narrative review of the regulatory framework.

Journal of Biomedical Practitioners
OBJECTIVE The growing volume of scientific research and the increasing methodological complexity of clinical trials have made a robust ethical and regulatory framework essential; however, some uncertainties persist.
Elisa Piccolo, Agnese Frola, Jonathan Nora, Irene Nieri, Luigi Collovà, Claudio Pobbiati, Domenico Riccardo Cammisa, Francesco Paolo Sellitti   +7 more
doaj   +1 more source

Research Ethics Committees

Ethics committees represent a “way of doing bioethics” that is useful in plural and democratic societies. Although there are different types of ethics committees, clinical ethics committees, national ethics committees or ad hoc committees, I will focus ...
Lecuona Ramírez, Itziar de
core   +1 more source

Empirical Assessments of Clinical Ethics Services: Implications for Clinical Ethics Committees

, 2007
The need to evaluate the performance of clinical ethics services is widely acknowledged although work in this area is more developed in the United States.
Williamson, L, Williamson, Laura
core   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Ethical issues in clinical research

Indian Journal of Plastic Surgery, 2007
Thatte Urmila
doaj   +1 more source

Ethics committees and clinical centers by geographical regions (December 2015).

, 2019
Ethics committees and clinical centers by geographical regions (December 2015).
Luca Ghirotto (8201202), Roberto Satolli (29435), Marta Perin (8201199), Ludovica De Panfilis (8201193), Massimo Costantini (3522176), Domenico Franco Merlo (8201196)   +5 more
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Treatment of patellofemoral osteoarthritis with nasal chondrocyte-based engineered cartilage implantation in a randomised, controlled, multicentre phase II clinical trial: protocol for a randomised controlled trial

BMJ Open
Introduction Knee osteoarthritis often starts in the patellofemoral compartment of the knee and is diagnosed in about 39% of people with knee pain aged above 30 years. Patellofemoral osteoarthritis plays a crucial role in the reduction of quality of life
Corina Schuster-Amft, Marcus Mumme, Sabine Schaedelin, Sarina Seitz, Gyözö Lehoczky, Anke Wixmerten, Sylvie Miot, Kristin Shrestha, Ivan Martin   +8 more
doaj   +1 more source

What Is Happening During Case Deliberations in Clinical Ethics Committees? A Pilot Study

, 2009
BACKGROUND: Clinical ethics consultation services have been established in many countries during recent decades. An important task is to discuss concrete clinical cases. However, empirical research observing what is happening during such deliberations is
Pedersen, Reodar, Førde, R., Akre, V.
core   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source