Results 111 to 120 of about 636,139 (316)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Tiempo de evolución de la apendicitis y riesgo de perforación Time and risk of rupture in acute appendicitis

open access: yesRevista Colombiana de Cirugía, 2013
Introducción. La apendicitis es la condición quirúrgica más común a la que se enfrenta el cirujano. La relación entre el tiempo de evolución y la complicación (perforación o peritonitis) se ha asumido como lineal, sin que exista evidencia contundente de ...
Álvaro Sanabria   +5 more
doaj  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Clinical Evolution After Administering Antivenom in Patients With Loxoscelism. [PDF]

open access: yesJ Med Cases, 2023
Azuara-Antonio O   +5 more
europepmc   +1 more source

The Role of Artificial Intelligence in the Evolution of Clinical and Diagnostic Microbiology: A Systematic Review

open access: yes
Conventional microbial diagnostic techniques encounter considerable obstacles, such as prolonged turnaround times, labor-intensive protocols, and constraints in precision.
Gautamkumar Dhokia   +3 more
core   +1 more source

Evolution of clinical signs and predictors of outcome after conservative medical treatment for disk-associated cervical spondylomyelopathy in dogs

open access: yes, 2012
Objective-To evaluate the evolution of clinical signs and their correlation with results of magnetic resonance imaging (MRI) and transcranial magnetic stimulation (TMS) and to assess potential prognostic variables after conservative medical treatment for
Van Ham, Luc M. L.   +11 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Clinical evolution of monkeypox lesions

open access: yesQJM: An International Journal of Medicine, 2022
A Ordinola Navarro   +3 more
openaire   +2 more sources

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