Results 91 to 100 of about 8,806,762 (263)

Report on administration of the 1990 examinations

open access: yes, 1990
The report of the twelfth year of administration of the Caribbean Examination Council (CXC) examinations deals separately with the two sittings of the examination – January and May/June.
Caribbean Examination Council Headquarters
core   +1 more source

Novel Insights into the Interaction between Enteropathogenic Bacteria, Pyroptosis and IBD

open access: yesFrontiers in Bioscience-Landmark
Inflammatory bowel disease (IBD) is a chronic and recurrent inflammatory disease of the intestinal tract. The complex pathophysiological mechanisms of IBD include genetic susceptibility, environmental factors, and abnormal immune response of the gut ...
Zhengyang Bao   +3 more
doaj   +1 more source

Diagnosis and staging of patients with ovarian cancer: National Clinical Guideline No. 20 Annex 1: Systematic review of cost effectiveness

open access: yes, 2018
The purpose of this systematic review was to identify and evaluate economic evidence to inform the clinical recommendations of this NCG. Review of the cost-effectiveness of health technologies enables guideline developers to explicitly consider how ...
HRB-CICER (Collaboration in Ireland for Clinical Effectiveness Reviews)
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

A guide to the clinical examination of the blood for diagnostic purposes /

open access: yes, 1897
Each plate accompanied by leaf with descriptive letter press.Spine title: Clinical examination of the blood.Includes index.Bibliography: p. 349-396.Book II: The primary anaemias -- Leukaemia and Hodgkin's Disease -- Pneumonia of fever on the blood ...
Cabot, Richard C. (Richard Clarke), 1868-1939.
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Kynurenic acid mediates epicardial fat-induced lymphatic metabolic dysfunction in atrial fibrillation

open access: yesNature Communications
Atrial fibrillation represents a prevalent cardiac arrhythmia whose pathogenic mechanisms remain incompletely understood. Here, we identify impaired atrial lymphangiogenesis as a critical determinant in atrial fibrillation pathogenesis. Analysis of human
Masaki Takahashi   +24 more
doaj   +1 more source

Evaluation of Diagnostic Values of Clinical Assessment in Determining the Maturation of Arteriovenous Fistulas for Satisfactory Hemodialysis

open access: yesAdvanced Biomedical Research, 2017
Background: Fistulas are the preferred permanent hemodialysis vascular access, but a significant obstacle to increasing their prevalence is the fistula's high “failure to mature” (FTM) rate.
Fereshteh Salimi   +5 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Prevalence and Ecological Role of Streptococcus toyakuensis in Saliva of Healthy Young Individuals

open access: yesInternational Dental Journal
Background and Objectives: Antimicrobial resistance (AMR) remains a critical global health concern. In 2022, Streptococcus toyakuensis, a newly identified species with potential multidrug resistance, was isolated from the blood of a patient with sepsis ...
Nami Obayashi   +11 more
doaj   +1 more source

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