Results 71 to 80 of about 8,806,762 (263)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Seven‐Day Patch ECG Monitoring During National Insurance Health Checkup Efficiently Detected Silent Atrial Fibrillation in Individuals Aged 75 Years and Older

Annals of Noninvasive Electrocardiology
Background It is unclear to what extent silent atrial fibrillation (AF) is present in subjects previously undiagnosed with AF. The recently popular 7‐day patch electrocardiography (ECG) monitoring may help answer this question. Methods In the Kitsuki and
Miho Miyoshi, Nozomi Kodama, Hiroki Sato, Kazuhiro Masutomo, Hitoshi Kamiunten, Tetsuji Shinohara, Naohiko Takahashi   +6 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

HMOX1 interacts with BNIP3 to modulate neuronal ferroptosis after spinal cord ischemia-reperfusion injury via a mitophagy-dependent mechanism

Cell Death Discovery
Spinal cord ischemia-reperfusion injury (SCIRI) is a severe secondary complication of trauma, spinal cord decompression, and thoracoabdominal aortic surgery.
Yanni Duan, Yibao Zhang, Fengguang Yang, Mingtao Zhang, Yujun Shi, Zongyan Ma, Xingxing Huang, Wen Li, Yun Lang, Xuchang Hu, Xuewen Kang   +10 more
doaj   +1 more source

THE ROLE OF CYTOLOGICAL STUDIES IN THE MEDICAL PRACTICE OF A PHYSICIAN WHEN DOCUMENTING CASES OF SEXUAL VIOLENCE

Медична наука України
Background. In Ukraine, in the context of international armed conflict, there is a tendency to focus on European standards when investigating cases of physical, psychological and sexual violence against civilians.
O.P. Babkina, I.V. Kholodilova
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Clinical Pharmacokinetics of Systemically Administered Antileishmanial Drugs [PDF]

, 2017
This review describes the pharmacokinetic properties of the systemically administered antileishmanial drugs pentavalent antimony, paromomycin, pentamidine, miltefosine and amphotericin B (AMB), including their absorption, distribution, metabolism and ...
Schellens, Jan H M, Dorlo, Thomas P. C.,, Kip, Anke E., Thomas P. C. Dorlo, Kip, Anke E, Schellens, Jan H. M., Beijnen, Jos H., Beijnen, Jos H.,, Schellens, Jan H. M.,, Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Dorlo, Thomas P. C., Dorlo, Thomas P C, Anke E. Kip, Kip, Anke E.,, Jos H. Beijnen, Beijnen, Jos H, Jan H. M. Schellens   +17 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

HSE Post mortem examination

, 2023
The purpose of the HSE National Clinical Guidelines for Post Mortem Examination Services (2023) is to build on the previous standards from 2012 and outline recommended practices required in post mortem examination services, based on current legal ...
HSE Guidelines for Post Mortem Examination Services: Review Group
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source