Resting-state connectivity and tobacco smoking in clinical high-risk for psychosis (NAPLS-3). [PDF]
Koster M +7 more
europepmc +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Clinical Factors Influencing Improvement in Disorganization in Clinical High-Risk for Psychosis: Preliminary Findings From a 2-Year Follow-Up. [PDF]
Pelizza L +10 more
europepmc +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Feasibility of a Stepped-Care Intervention for Those at Clinical High Risk for Psychosis in the United States. [PDF]
Shapiro DI +18 more
europepmc +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Clinical Considerations of the High-risk Patient [PDF]
openaire +1 more source
Reduced interpersonal head synchrony in youth at clinical high risk for psychosis. [PDF]
Lozano-Goupil J +12 more
europepmc +1 more source
Glutamate, NAA, and energy metabolism in clinical high risk and first episode psychosis. [PDF]
King B +4 more
europepmc +2 more sources
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source

