Results 41 to 50 of about 5,841,868 (306)

Comprehensive review of multidimensional biomarkers in the ShangHai At Risk for Psychosis (SHARP) program for early psychosis identification

PCN Reports, 2023
Psychosis is recognized as one of the largest contributors to nonfatal health loss, and early identification can largely improve routine clinical activity by predicting the psychotic course and guiding treatment.
TianHong Zhang, LiHua Xu, XiaoChen Tang, YanYan Wei, YeGang Hu, HuiRu Cui, YingYing Tang, ChunBo Li, JiJun Wang   +8 more
doaj   +1 more source

Heterogeneity of Psychosis Risk Within Individuals at Clinical High Risk [PDF]

JAMA Psychiatry, 2016
Individuals can be classified as being at clinical high risk (CHR) for psychosis if they meet at least one of the ultra-high-risk (UHR) inclusion criteria (brief limited intermittent psychotic symptoms [BLIPS] and/or attenuated psychotic symptoms [APS] and/or genetic risk and deterioration syndrome [GRD]) and/or basic symptoms [BS]. The meta-analytical
Fusar-Poli P., Cappucciati M., Borgwardt S., Woods S. W., Addington J., Nelson B., Nieman D. H., Stahl D. R., Rutigliano G., Riecher-Rossler A., Simon A. E., Mizuno M., Lee T. Y., Kwon J. S., Lam M. M. L., Perez J., Keri S., Amminger P., Metzler S., Kawohl W., Rossler W., Lee J., Labad J., Ziermans T., An S. K., Liu C. -C., Woodberry K. A., Braham A., Corcoran C., McGorry P., Yung A. R., McGuire P. K.   +31 more
openaire   +9 more sources

Targeting tachykinin receptors in neuroblastoma [PDF]

, 2016
Neuroblastoma is the most common extracranial tumor in children. Despite aggressive multimodal treatment, high-risk neuroblastoma remains a clinical challenge with survival rates below 50%.
Althoff, Kristina, Astrahanseff, Kathy, Beckers, Anneleen, Bergmann, Andreas, De Preter, Katleen, Eggert, Angelika, Henssen, Anton G, Odersky, Andrea, Schramm, Alexander, Schulte, Johannes H, Schäfers, Simon, Seiler, Marleen, Speleman, Franki, Struck, Joachim, Szymansky, Annabell   +14 more
core   +3 more sources

Access to Care and Cardiovascular Disease Prevention: A Cross-Sectional Study in 2 Latino Communities. [PDF]

, 2015
Cardiovascular disease (CVD) is the leading killer of Americans. CVD is understudied among Latinos, who have high levels of CVD risk factors. This study aimed to determine whether access to health care (ie, insurance status and having a usual source of ...
Albert, Stephanie L, Alcalá, Héctor E, Beckerman, Jacob, Brookmeyer, Ron, Champagne, Philippe, Garcia, Rosa-Elenna, Glik, Deborah C, Inkelas, Moira, Ortega, Alexander N, Prelip, Michael L, Roby, Dylan H   +10 more
core   +1 more source

Effects of omega-3 polyunsaturated fatty acid supplementation on cognitive functioning in youth at ultra-high risk for psychosis: secondary analysis of the NEURAPRO randomised controlled trial

BJPsych Open, 2022
Background Cognitive impairments are well-established features of psychotic disorders and are present when individuals are at ultra-high risk for psychosis. However, few interventions target cognitive functioning in this population.
Nicholas Cheng, Alison McLaverty, Barnaby Nelson, Connie Markulev, Miriam R. Schäfer, Maximus Berger, Nilufar Mossaheb, Monika Schlögelhofer, Stefan Smesny, Ian B. Hickie, Gregor E. Berger, Eric Y. H. Chen, Lieuwe de Haan, Dorien H. Nieman, Merete Nordentoft, Anita Riecher-Rössler, Swapna Verma, Rebekah Street, Andrew Thompson, Hok Pan Yuen, Robert Hester, Alison Ruth Yung, Patrick D. McGorry, Kelly Allott, G. Paul Amminger   +24 more
doaj   +1 more source

Imipramine blue sensitively and selectively targets FLT3-ITD positive acute myeloid leukemia cells. [PDF]

, 2017
Aberrant cytokine signaling initiated from mutant receptor tyrosine kinases (RTKs) provides critical growth and survival signals in high risk acute myeloid leukemia (AML).
Arbiser, Jack L, Bradley, Heath L, Bunting, Kevin D, Kapur, Reuben, Metts, Jonathan, Shah, Neil P, Wang, Zhengqi   +6 more
core   +1 more source

Clinical high-risk criteria of psychosis in 8- to 17-year-old community subjects and inpatients not suspected to develop psychosis: not pluripotential or transdiagnostic

European Psychiatry, 2022
Introduction Based on high rates of non-converters to psychosis, especially in children and adolescents, it was suggested that CHR criteria were (1) pluripotential, (2) a transdiagnostic risk factor, or (3) simply a severity marker of mental disorders ...
F. Schultze-Lutter, C. Michel, M. Franscini, N. Traber-Walker, P. Walger, B. Schimmelmann   +5 more
doaj   +1 more source

High-Risk Breast Clinic

Journal of the Advanced Practitioner in Oncology
Individuals who are at a high risk for breast cancer are a unique population. These women and men may be eligible for additional screenings for breast cancer and require education that can help reduce the risk of breast cancer. There are several risk factors, such as smoking and obesity, that can be modifiable to help reduce the risk for developing ...
Doubleday, Erica S., Alker, Peggy Jo
openaire   +2 more sources

A Quality Improvement Initiative to Standardize Pneumocystis jirovecii Pneumonia Prophylaxis in Pediatric Patients With Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar, Denise M. Connolly, Ellen Kellington, Elyse Zelunka, Karla Kerrigan, Furqan Shaikh, Paul C. Nathan, Meredith S. Irwin, Sarah Cohen‐Gogo   +8 more
wiley   +1 more source

Successful Management by Selective Embryo in the Carnitine-acylcarnitine Translocase Deficiency with SLC25A20 C.199-10T>G Variation: The First Case Report from Vietnam and Literature Review

Oman Medical Journal
Carnitine-acylcarnitine translocase deficiency with SLC25A20 c.199-10T>G variation is a rare condition, typically associated with severe neonatal outcomes.
Ngoc Bich Trinh, Anh Dinh Bao Vuong, Phuc Nhon Nguyen   +2 more
doaj   +1 more source