Results 31 to 40 of about 428,100 (253)

Findings Related to Cerebrospinal Fluid and Central Nervous System Disorders in Small Ruminants—A Retrospective Study on Sheep and Goats

Animals, 2023
Background: Small ruminants often suffer from central nervous system (CNS) disorders, and cerebrospinal fluid (CSF) analysis can be used as a diagnostic tool in this regard.
Leandra C. Schöb, Christian Gerspach, Martina Stirn, Regina Hofmann-Lehmann, Barbara Riond   +4 more
doaj   +1 more source

Quality Clinical Laboratory Services for the American People [PDF]

Public Health Reports (1896-1970), 1970
A LTHOUGH those close to the clinical laboratory have long recognized that laboratory errors can occur, the problem has not been openly discussed until recently. Walter Cronkite in a Columbia Broadcasting System program in 1965 focused lattention on the poor performance of certain mail-order laboratories and stimulated, in part, the introduction of ...
openaire   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

C-terminal domain small phosphatase 1 (CTDSP1) regulates growth factor expression and axonal regeneration in peripheral nerve tissue

Scientific Reports, 2021
Peripheral Nerve Injury (PNI) represents a major clinical and economic burden. Despite the ability of peripheral neurons to regenerate their axons after an injury, patients are often left with motor and/or sensory disability and may develop chronic pain.
Noreen M. Gervasi, Alexander Dimtchev, Desraj M. Clark, Marvin Dingle, Alexander V. Pisarchik, Leon J. Nesti   +5 more
doaj   +1 more source

Characterization of the services of the private clinical laboratories of Ambato.

Medwave, 2023
Introducción La investigación tubo como finalidad caracterizar los servicios privados de laboratorio clínico del Cantón Ambato, siendo los principales beneficiarios los profesionales que realizan el papel administrativo, de control de calidad y los pacientes que hacen uso de los servicios.
Martha Cecilia Ramos Ramìrez, Gardenia Alexandra Pérez Balseca, Edison Arturo Galarraga Pèrez   +2 more
openaire   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Delivering clinical laboratory services to intensive care units [PDF]

Clinical Chemistry, 1996
Abstract In response to the pressures of cost reduction, we established and evaluated a carefully integrated program to deliver clinical laboratory services more promptly and efficiently to the intensive care units (ICUs). The new protocol reduced the steps and turnaround time from ordering tests by physicians to reporting results by as ...
M W, Steffes, J L, Gillen, S A, Fuhrman
openaire   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

The impact of symptom duration on D-dimer: results from the Venous Thrombosis Registry in Østfold Hospital

Research and Practice in Thrombosis and Haemostasis
Background: It has been suggested that D-dimer testing should be avoided in patients with prolonged symptoms, as results may yield false negatives. However, the evidence supporting this recommendation is limited.
Mazdak Tavoly, Camilla Tøvik Jørgensen, Katarina Glise Sandblad, Waleed Ghanima, Lamya Garabet   +4 more
doaj   +1 more source