Results 121 to 130 of about 734,729 (308)
The Centers for Disease Control and Prevention\u2019s (CDC) Division of Laboratory Systems (DLS) works to advance quality and safety systems, informatics and data science, and training and workforce development.
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Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Recent advances in the detection technologies for balanced chromosomal rearrangements
Frontiers in GeneticsBalanced chromosomal rearrangements (BCRs) refer to a type of chromosomal structural variations without chromosomal gains or losses. BCR carriers may experience fertility issues, including a higher risk of infertility, recurrent miscarriages, or having ...
Meng Gao +5 more
doaj +1 more source
CDC INFECTIOUS DISEASES LABORATORY TEST DIRECTORY : 2024, Version 17.1
This document was created under Center for Laboratory Systems and Response (CLSR). The printed version of CDC's Infectious Diseases Laboratory Test Directory contains information that is current as of January 19, 2024. All information contained herein is
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Self-assessment checklist for good testing practices [PDF]
The following self-assessment checklist emphasizes recommended practices for physicians, nurses, medical assistants, pharmacists, and others who perform patient testing under a Clinical Laboratory Improvement Amendments (CLIA) Certificate of Waiver.
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FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Interim guidelines for biosafety and COVID-19 : interim laboratory biosafety guidelines for handling and processing specimens associated with coronavirus disease 2019 (COVID-19) [PDF]
Updated Aug. 11, 2020Until more information becomes available, precautions should be taken in handling specimens that are suspected or confirmed for SARS-CoV-2.
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Provider performed microscopy procedures : a focus on quality practices [PDF]
Health care providers use laboratory test results to diagnose disease, determine prognosis, and monitor a patient\u2019s treatment or health status. Current practice shows an increased trend for medical decisions based on tests performed at the point of ...
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FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source