Results 41 to 50 of about 878,073 (326)

COVID-19: laboratory diagnosis for clinicians. An updating article

São Paulo Medical Journal, 2020
COVID-19 (coronavirus disease 2019) is an infectious disease caused by the new coronavirus associated with severe acute respiratory syndrome 2 (SARS-CoV-2).
Luisane Maria Falci Vieira, Eduardo Emery, Adagmar Andriolo   +2 more
doaj   +1 more source

Eulerian Phase-based Motion Magnification for High-Fidelity Vital Sign Estimation with Radar in Clinical Settings [PDF]

arXiv, 2022
Efficient and accurate detection of subtle motion generated from small objects in noisy environments, as needed for vital sign monitoring, is challenging, but can be substantially improved with magnification. We developed a complex Gabor filter-based decomposition method to amplify phases at different spatial wavelength levels to magnify motion and ...
arxiv  

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

Measurement of Human Chorionic Gonadotrophin (hCG): Indications and Techniques for the Clinical Laboratory [PDF]

Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1990
The structure of human chorionic gonadotrophin (hCG) is so similar to that of luteinizing hormone (LH) that a variety of assay techniques have been devised to differentiate between these two hormones. The principal indications for measurement of hCG using these methods have not changed greatly over the past decade but the improvements in the ...
Robert J. Norman, S. F. de Medeiros, R H Buck   +2 more
openaire   +2 more sources

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

Molecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren, Philippe Decruyenaere, Francisco Avila Cobos, Johanna Bult, Jill Deleu, Laudonia Lidia Dipalo, Hetty Hilde Helsmoortel, Eva Hulstaert, Annelien Morlion, Elena Ramos Varas, Kathleen Schoofs, Wim Trypsteen, Eveline Vanden Eynde, Hanne Van Droogenbroeck, Kimberly Verniers, Jo Vandesompele, Anneleen Decock   +16 more
wiley   +1 more source

MLKL is involved in the regulation of skin wound healing and interplay between macrophages and myofibroblasts in mice

Scientific Reports
Mixed lineage kinase domain-like protein (MLKL), a critical necroptosis effector, is strongly linked to inflammation, a key component of skin wound healing. However, its precise role in the wound healing process remains inadequately characterized.
Jiamin Zhao, Shuangyi Zhang, Yunjie Bai, Zhiguo Gong, Wenhui Bao, Zhuoya Yu, Bo Liu, Wei Mao, Surong Hasi   +8 more
doaj   +1 more source

TLR2 and NLRP3 Orchestrate Regulatory Roles in Escherichia coli Infection-Induced Septicemia in Mouse Models

Journal of Innate Immunity
Introduction: Escherichia coli (E. coli) is a significant commensal gram-negative bacterium that can give rise to various diseases. The roles of Toll-like receptor 2 (TLR2) and the NOD-like receptor pyrin domain-containing protein 3 (NLRP3) inflammasome ...
Zhiguo Gong, Wei Mao, Jiamin Zhao, Peipei Ren, Zhuoya Yu, Yunjie Bai, Chao Wang, Yuze Liu, Shuang Feng, Surong Hasi   +9 more
doaj   +1 more source

Evaluation of multiplex ARMS-PCR for detection of Helicobacter pylori mutations conferring resistance to clarithromycin and levofloxacin

Gut Pathogens, 2020
Background Helicobacter pylori bacterium is a major cause of gastritis. With increasing use of antibiotics to treat infections, mutation resistant strains have emerged in most human populations.
Yangxia Li, Tangshan Lv, Chaochao He, Hongyan Wang, David S. Cram, Linfu Zhou, Jun Zhang, Weiqin Jiang   +7 more
doaj   +1 more source

Why Test study protocol: a UK-wide audit using the Primary Care Academic CollaboraTive (PACT) to explore the reasons for primary care testing

BJGP Open, 2022
Background: The number of blood tests done in primary care has been increasing over the past 20 years. Some estimates suggest that up to one-quarter of these tests may not have been needed.
Alexander Burrell, Polly Duncan, Ian Bennett-Britton, Sam Hodgson, Samuel WD Merriel, Salman Waqar, Penny Whiting, Jessica Watson, on behalf of the Primary Care Academic Collaborative (PACT)   +8 more
doaj   +1 more source

Clinical connectivity map for drug repurposing: using laboratory tests to bridge drugs and diseases [PDF]

arXiv, 2020
Drug repurposing has attracted increasing attention from both the pharmaceutical industry and the research community. Many existing computational drug repurposing methods rely on preclinical data (e.g., chemical structures, drug targets), resulting in translational problems for clinical trials.
arxiv