Results 61 to 70 of about 2,113,439 (265)

Long‐Term Outcomes of Patients With Relapsed/Refractory Neuroblastoma Treated on ANBL1221: A Report From the Children's Oncology Group

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Results of COG ANBL1221 changed treatment paradigms for patients with relapsed/refractory neuroblastoma. Chemoimmunotherapy with irinotecan/temozolomide/dinutuximab is now used as both bridge therapy following suboptimal response to induction and as treatment in first relapse.
Elizabeth Sokol, Arlene Naranjo, Lulu Chen, Rajen Mody, Steven G. DuBois, Rochelle Bagatell, Navin Pinto   +6 more
wiley   +1 more source

Contact precautions prevent cross-contamination of extended-spectrum beta-lactamase-producing Enterobacterales in an intensive care unit: a prospective observational study

Annals of Intensive Care
Background: The spread of multidrug-resistant microorganisms (MDROs), including extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-E), has increased worldwide and constitutes a significant public health challenge.
Nina Milerad, Christina Agvald Öhman, Inga Fröding, Christian G. Giske, Markus Castegren   +4 more
doaj   +1 more source

BMT4me En Español: Multisite Feasibility and Usability Testing of a Spanish‐Language mHealth Adherence Support App for Spanish‐Speaking Caregivers of Children After Hematopoietic Stem Cell Transplantation and Cancer Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Medication nonadherence during the first 100 days after pediatric hematopoietic stem cell transplantation (HSCT) and during oncology treatment increases risk for complications. BMT4me is a caregiver‐facing mobile health (mHealth) application providing medication reminders, symptom tracking, and note‐taking features to support ...
Micah A. Skeens, Madeline R. Peek, Bianca Franklin, Emre Sezgin, Melissa Beauchemin   +4 more
wiley   +1 more source

Time-course changes in energy expenditure in sepsis: a prospective observational study

Annals of Intensive Care
Background: Sepsis is associated with dynamic metabolic alterations influencing energy expenditure and substrate utilization. This study aimed to evaluate time-course changes in energy metabolism in critically ill patients with sepsis and identify ...
Weronika Wasyluk, Robert Fiut, Izabela Świetlicka, Magdalena Szukała, Agnieszka Zwolak, Joop Jonckheer, Wojciech Dąbrowski   +6 more
doaj   +1 more source

Measurable Residual Disease Monitoring During Treatment for Pediatric Acute Myeloid Leukemia in First Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survival after relapse in pediatric acute myeloid leukemia (AML) remains poor, highlighting the critical importance of identifying prognostic factors to guide optimal relapse management. Methods We investigated the prognostic impact of multiparameter flow cytometry (MFC) measurable residual disease (MRD) in 188 patients with first ...
Camilla Poulsen, Kristian Juul Sandahl, Lene Karlsson, Jonas Abrahamsson, Nira Arad‐Cohen, Daniel Cheuk, Barbara De Moerloose, Linda Fogelstrand, Jose Maria Fernandez Navarro, Bianca F. Goemans, Kirsi Jahnukainen, Gertjan Kaspers, Zhanna Kovalova, Monica Cheng Munthe‐Kaas, Ulrika Norén‐Nyström, Josefine Palle, Ramune Pasauliene, Cornelis Jan Pronk, Kadri Saks, Anne Tierens, Henrik Hasle, Kristian Løvvik Juul‐Dam   +21 more
wiley   +1 more source

Urinary 3-methylhistidine as a potential biomarker for sepsis-associated acute kidney injury: multidimensional metabolomics analysis in mice and human

Annals of Intensive Care
Background: Sepsis-associated acute kidney injury (SA-AKI) is strongly associated with increased mortality in critical patients. The early detection of SA-AKI is crucial for clinical intervention.
Xibo Wang, Pengfei Huang, Yinghao Luo, Yu Xin, Yue Li, Lifeng Shen, Yanqi Liu, Yang Zhou, Yuxin Zhang, Qianqian Zhang, Dawei Wang, Feiyu Luan, Weiting Zhang, Mengyao Yuan, Yuhan Liu, Fengye Liu, Nan Zhang, Jinyuan Wu, Tao Wu, Xuan Wang, Yuping Bai, Mingyan Zhao, Changsong Wang, Kaijiang Yu   +23 more
doaj   +1 more source

Factors associated with ICU mortality and long-term outcomes in immunocompromised patients admitted to the intensive care unit for acute respiratory failure

Annals of Intensive Care
Background: Mortality of immunocompromised patients is particularly high in intensive care units (ICUs) and mainly depends on severity at admission. Moreover, mortality is also high during the months following ICU discharge.
Mélanie Métais, Jean-Pierre Frat, Stephan Ehrmann, Frédéric Pène, Maxens Decavèle, Nicolas Terzi, Gwenaël Prat, Maëlle Martin, Damien Contou, Arnaud Gacouin, Jeremy Bourenne, Christophe Girault, Christophe Vinsonneau, Jean Dellamonica, Guylaine Labro, Sébastien Jochmans, Alexandre Herbland, Jean-Pierre Quenot, Jérôme Devaquet, Dalila Benzekri, Stéphanie Ragot, Arnaud W. Thille, Rémi Coudroy, Emmanuel Vivier, Saad Nseir, Gwenhaël Colin, Didier Thevenin, Giacomo Grasselli, David Bougon, Mona Assefi, Claude Guérin, Thierry Lherm, Achille Kouatchet   +32 more
doaj   +1 more source

From the Editor: Medical Social Science and Clinical Decision Science

Clinical Research In Practice: The Journal of Team Hippocrates, 2020
Exploring the curricular link between Medical Social Science and Clinical Decision Science in the development of a physician.
openaire   +2 more sources

T2* Magnetic Resonance Imaging Uncovers Hemosiderin Burden in Pediatric Hemophilia: A Call for Sensitive Imaging Biomarkers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hemophilic arthropathy remains the leading morbidity in hemophilia despite modern prophylaxis, and early joint damage may be missed by routine exams. This study explored T2* MRI as a noninvasive biomarker of hemosiderin deposition in pediatric hemophilia.
Jessica Garcia, Tarique Hussain, Jeanne Dillenbeck, Matthew Hammer, Annette von Drygalski, Guy Young, Ayesha Zia   +6 more
wiley   +1 more source

Diagnostic yield and adverse events of liver biopsy in intensive-care-unit patients: a multicenter retrospective observational cohort study

Annals of Intensive Care
Background: To investigate the adverse events, diagnostic yield, and therapeutic implications of liver biopsy in intensive-care-unit (ICU) patients. Methods: Retrospective observational multicenter cohort study.
Mégane Charrier, Jean-Claude Lacherade, Lara Zafrani, Jérôme Hoff, Jean Reignier, Jean-Baptiste Lascarrou, Jean-François Mosnier, Emmanuel Canet   +7 more
doaj   +1 more source