Results 181 to 190 of about 17,654,627 (326)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Serial Lactate in Clinical Medicine - A Narrative Review. [PDF]

J Intensive Care Med
Falter F, Tisherman SA, Perrino AC, Kumar AB, Bush S, Nordström L, Pathan N, Liu R, Mebazaa A.   +8 more
europepmc   +1 more source

Clinical Laboratory Medicine [PDF]

, 2006
仁井見 英樹, 北島 勲, 大塚 稔久, 岩城 有佳   +3 more
core   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

THE 70TH ANNIVERSARY OF EMINENT SCIENTIST, TALENTED DOCTOR-CARDIOLOGIST KRAVCHUN PAVLO GRYGOROVICH IS DEDICATED

Journal of V. N. Karazin Kharkiv National University: Series Medicine, 2014
Department of Internal Medicine № 2, Clinical Immunology and Allergology
doaj  

Bridging Genomics and Clinical Medicine: RSVrecon Enhances RSV Surveillance With Automated Genotyping and Clinically Important Mutation Reporting. [PDF]

Influenza Other Respir Viruses
Li L, Yi H, Brazelton JN, Webby RJ, Hayden RT, Wu G, Hijano DR.   +6 more
europepmc   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Editorial: Contemporary Medicine: Making Sense of Implementation Models and Methods

Frontiers in Medicine, 2022
Michele M. Ciulla, Michele M. Ciulla, Ugo Cioffi   +2 more
doaj   +1 more source

Therapeutic progress in leptomeningeal metastasis from EGFR mutant non-small cell lung cancer: a clinical medicine review. [PDF]

J Cancer Res Clin Oncol
Ding T, Xie Y, Ding M.
europepmc   +1 more source

Clinical Forensic Medicine [PDF]

Academic Emergency Medicine, 1995
openaire   +2 more sources