Results 61 to 70 of about 16,573,156 (294)

The When, What & How of Measuring Vitamin D Metabolism in Clinical Medicine

open access: yesNutrients, 2018
We now have the ability to measure a number of different vitamin D metabolites with very accurate methods. The most abundant vitamin D metabolite, 25-hydroxyvitamin D, is currently the best marker for overall vitamin D status and is therefore most ...
N. Dirks   +6 more
semanticscholar   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Sustainable development of electroencephalography materials and technology

open access: yesSusMat
Electroencephalogram (EEG) is one of the most important bioelectrical signals related to brain activity and plays a crucial role in clinical medicine.
Ling Xiong, Nannan Li, Yi Luo, Lei Chen
doaj   +1 more source

Professor J.J. Plenk — founder of world scientific dermatology. [PDF]

open access: yesСаратовский научно-медицинский журнал, 2016
The article presents the biography of Professor J. J. Plenck and his scientific and practical contribution to the development of European clinical medicine in the second half of the 18th century and in the establishment of world scientific dermatology.
Betechtin M.S., Zavyalov A.l.
doaj  

Precision dosing in clinical medicine: present and future

open access: yesExpert Review of Clinical Pharmacology, 2018
There are four potential outcomes when a patient commences a newdrug and its effects are assessed at the correct time. First, the new drug provides no clinical benefits and gives the patient intolerable adverse effects (negative benefit: risk).
T. Polasek   +2 more
semanticscholar   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Artificial Intelligence (AI)-aided Disease Prediction

open access: yesBIO Integration, 2020
Artificial intelligence (AI) has been widely used in clinical medicine, and it is witnessing increasing innovations in the fields of AI-aided image analysis, AI-aided lesion determination, AI-assisted healthcare management, and so on. This review article
Chenxi Liu, Dian Jiao, Zhe Liu
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Development of scoring system for risk stratification in clinical medicine: a step-by-step tutorial.

open access: yesAnnals of Translational Medicine, 2017
Risk scores play an important role in clinical medicine. With advances in information technology and availability of electronic healthcare record, scoring systems of less commonly seen diseases and population can be developed.
Wentao Bao   +2 more
semanticscholar   +1 more source

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