Results 101 to 110 of about 6,471,944 (292)

Biomedical mass spectrometry in today's and tomorrow's clinical microbiology laboratories

open access: yes, 2012
Clinical microbiology is a conservative laboratory exercise where base technologies introduced in the 19th century remained essentially unaltered. High-tech mass spectrometry (MS) has changed that.
Chatellier, S. (Sonia)   +7 more
core   +1 more source

Artificial Intelligence‐Empowered Single‐Cell Phenotyping for Rapid, Automated Pathogen Diagnostics

open access: yesAdvanced Science, EarlyView.
This work presents an integrated diagnostic platform that combines microfluidic single‐cell bacterial detection with artificial intelligence‐driven analysis for rapid antimicrobial susceptibility testing. Single‐cell phenotyping enables assessment of antibiotic response in only a few cell replication cycles, while AI analysis supports precise bacterial
Sabita Khadka   +3 more
wiley   +1 more source

Evaluation of Group B Streptococcus culture processing using a commercial flocked swab with and without automated sample processing instrument

open access: yesMicrobiology Spectrum
Group B Streptococcus (GBS) is the most common cause of neonatal sepsis. Screening for vaginal-rectal colonization of the mother is important to prevent exposure.
Richard D. Smith   +2 more
doaj   +1 more source

Microbiology

open access: yes, 2017
"Microbiology is a peer reviewed, openly licensed introductory textbook produced through a collaborative publishing agreement between OpenStax and the American Society for Microbiology Press"--Page 4 of cover."Microbiology covers the scope and sequence ...
Schneegurt, Mark A.   +4 more
core  

Advances Afoot in Microbiology

open access: yes, 2017
In 2016, the American Academy of Microbiology convened a colloquium to examine point-of-care (POC) microbiology testing and to evaluate its effects on clinical microbiology.
Robin Patel, Brad S. Karon
core   +1 more source

Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy

open access: yesAdvanced Science, EarlyView.
Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song   +7 more
wiley   +1 more source

Deubiquitination of Vangl by USP6 and USP32 Regulates Planar Cell Polarity Signaling

open access: yesAdvanced Science, EarlyView.
Compartment‐specific deubiquitination controls Vangl dosage and planar cell polarity signaling. USP6 and USP32 regulate distinct subcellular pools of Vangl by removing distinct ubiquitin modifications from Vangl proteins. This regulatory mechanism safeguards PCP‐dependent embryonic morphogenesis, while aberrant USP32‐dependent stabilization of VANGL ...
Fangzi Zha   +13 more
wiley   +1 more source

Rapid prediction of carbapenemases in Pseudomonas aeruginosa by imipenem/relebactam and MALDI-TOF MS

open access: yesJournal of Clinical Microbiology
Pseudomonas aeruginosa is a major nosocomial pathogen commonly involved in multidrug-resistant (MDR) infections that are very difficult to treat. Imipenem/relebactam is a new carbapenem/β-lactamase inhibitor combination with robust activity against P ...
Ana Candela   +15 more
doaj   +1 more source

Radiation‐Triggered Chemokine‐Secreting Probiotics for Boron Neutron Capture Therapy Based Radioimmunotherapy

open access: yesAdvanced Science, EarlyView.
Engineered Escherichia coli Nissle 1917 with a tannic acid‐mediated BPA coating enables tumor‐targeted boron delivery for BNCT. The low‐level incidental radiation generated during BNCT activate a RecA‐driven circuit to induce CXCL10, while radiation‐enhanced bacterial colonization triggers in situ vaccination and systemic antitumor immunity.
Yang Liu   +11 more
wiley   +1 more source

Refining microbiome resolution: KoSCAPEbio identifies Klebsiella oxytoca complex species in16S rRNA amplicon data and uncovers associations with NEC

open access: yesGut Microbes
Klebsiella are early colonizers and commensals of human hosts but are also opportunistic pathogens. Research has focused on Klebsiella pneumoniae due to its global contribution to nosocomial infection and antibiotic resistance. Yet Klebsiella oxytoca and
Amar Cosic   +4 more
doaj   +1 more source

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