Results 101 to 110 of about 602,240 (294)

A Cationic Supramolecule With Potent Antifungal Activity, Single‐Species Selectivity, and Strong Synergy With Echinocandins

Advanced Science, EarlyView.
We introduce a new membrane‐active antifungal design, Gua‐SMACS‐16, that exhibits high potency and single‐species selectivity for C. tropicalis while sparing other close species in the Candida genus. Moreover, when combining with caspofungin, a clinical antifungal drug inhibiting 1,3‐β‐glucan synthase, they exhibit ultra‐strong synergy across a panel ...
Tianjiao Dai, Adrielle Xianwen Chen, Eve Wai Ling Chow, Li Mei Pang, Jianguo Li, Chandra Shekhar Verma, Stefan H. Oehlers, Yue Wang, Ning Li   +8 more
wiley   +1 more source

Rare Case of Psychrobacter Sanguinis Bacteremia in a Homeless Patient with Thigh Phlegmon

Postępy Mikrobiologii
Psychrobacter sanguinis is an emerging opportunistic pathogen predominantly isolated from cold environments that is increasingly recognized for its clinical relevance. This case report documents a rare instance of P. sanguinis bacteremia in a 69-year-old
Bielec Filip, Machnicki Piotr, Mikołajczyk-Solińska Melania, Kasznicki Jacek, Pastuszak-Lewandoska Dorota, Brauncajs Małgorzata   +5 more
doaj   +1 more source

Aptamer‐Directed Porous DNA Nanocomposite Hydrogel for Active Pulp Preservation: Immunomodulation, Stem Cell Recruitment and Reparative Dentinogenesis

Advanced Science, EarlyView.
This study presents an injectable DNA‐based porous hydrogel integrating catechol motifs and targeting aptamers for pulpitis management. Upon in situ crosslinking, the scaffold actively recruits endogenous dental pulp stem cells, restores redox homeostasis, and modulates immune responses.
Luhui Cai, Huan Yu, Zihan Ni, Kan Chen, I‐Chen Tsai, Zeyu Bao, Shuo Sun, Weichang Li, Yunhua Chen, Qiong Xu   +9 more
wiley   +1 more source

Metagenomic next-generation sequencing and conventional microbiology for microbial profiling in biliary tract infections: a comparative study with clinical stratification

Frontiers in Microbiology
BackgroundBiliary tract infections (BTIs) are clinically important conditions characterized by complex heterogeneous microbial profiles. However, the complete spectrum of implicated microorganisms, particularly anaerobic species and polymicrobial ...
Jianmin Ren, Ziling Lan, Cheng Wang, Jinnuo Zhu, Mei Li, Jianfen Xu, Yiyang Lu, Jianfei Tu, Xiaoyao Zhang, Lidija Boskovic, Jiansheng Huang, Jiansheng Huang, Xiaolei Hu, Xiaolei Hu   +13 more
doaj   +1 more source

Eco‐Geography Reverses Dominant AMR Reservoirs in Klebsiella pneumoniae: Integron‐Rich Mobilomes and Cross‐Niche Connectivity

Advanced Science, EarlyView.
Dominant antimicrobial resistance reservoirs in Klebsiella pneumoniae vary across eco‐geographic settings rather than following a universal pattern. Integrated One Health and global genomic analyses show that lineage structure, integron load, and cross‐niche connectivity shape whether AMR burden accumulates primarily in human or nonhuman compartments ...
Hui Lin, Biao Tang, Hao Xu, Jiajie Qian, Feifan Shi, Junhui Zhao, Xiaorui Mao, Xiaohe Hu, Ruishan Liu, Wenhong Liu, Xiawei Jiang, Beiwen Zheng, Guoping Zhao   +12 more
wiley   +1 more source

Automatic detection and quantification of antimicrobial inhibition zones using YOLO11n with post-hoc interpretability validation

Frontiers in Microbiology
IntroductionThe escalating prevalence of antimicrobial resistance (AMR) constitutes a global healthcare crisis, necessitating rapid and standardized diagnostic solutions for antimicrobial susceptibility testing (AST).
Fatih Ciftci, Fatih Ciftci, Fatih Ciftci, Azime Erarslan, Javad Rahebi   +4 more
doaj   +1 more source

Sulfated Cyclocarya Paliurus Polysaccharide Sorchestrates the Gut Microbiome to Mobilize a Host‐Derived 12‐HEPE Against Ulcerative Colitis

Advanced Science, EarlyView.
A sulfated polysaccharide (SCP) from Cyclocarya paliurus alleviates ulcerative colitis by reshaping the gut microbiome. This remodeled microbiota orchestrates the upregulation of the host‐derived lipid 12‐HEPE, which directly inhibits the TLR4/NF‐κB pathway to suppress inflammation.
Xianxiang Chen, Mingyue Shen, Rui Zhang, Zhibing Huang, Hui Niu, Qiang Yu, Yi Chen, Xiangwen Pan, Liyuan Rong, Huiliang Wen, Jun Yang, Jianhua Xie   +11 more
wiley   +1 more source

Clinical microbiology [PDF]

Journal of Hospital Infection, 1988
  +5 more sources

Planning for the future of the American Society for Microbiology’s Health Unit by the Council on Microbial Sciences

mSphere
In February and March 2025, the American Society for Microbiology (ASM)’s Council on Microbial Sciences (COMS) hosted a series of virtual retreats to integrate the communities of Clinical Infections and Vaccines (CIV) and Clinical and Public Health ...
Austin J. Fox, Andrea M. Prinzi, Nancy W. Wamburu, Nicholas M. Moore, Michael M. Lieberman, Kileen Shier, Nancy L. Haigwood   +6 more
doaj   +1 more source

Significance of Staphylococcus epidermidis in Health Care-Associated Infections, from Contaminant to Clinically Relevant Pathogen : This Is a Wake-Up Call!

, 2016
Coagulase-negative staphylococci, particularly Staphylococcus epidermidis, have been recognized as an important cause of health care-associated infections. Concurrently, S.
Widerström, Micael,
core   +1 more source