Results 31 to 40 of about 926,237 (299)

Antibiotic Treatment for Chronic Rhinosinusitis: Prescription Patterns and Associations With Patient Outcome and the Sinus Microbiota

Frontiers in Microbiology, 2020
BackgroundChronic rhinosinusitis (CRS) is a common and debilitating inflammatory condition of the sinuses, afflicting 5% of the general population. Although antibiotics are frequently prescribed for the medical management of CRS, there is surprisingly ...
Christian A. Lux, Christian A. Lux, Brett Wagner Mackenzie, James Johnston, Melissa Zoing, Kristi Biswas, Michael W. Taylor, Richard G. Douglas   +7 more
doaj   +1 more source

Multilocus sequence typing of Cronobacter spp. from powdered infant formula and milk powder production factories [PDF]

, 2013
This study applied the Cronobacter spp. multilocus sequence typing (MLST) scheme to three strain collections, then known as Enterobacter sakazakii, which had been isolated between 1988 and 2009 from 14 countries. The results revealed the predominance (85%
Craven, HM, Forsythe, SJ, Joseph, F, McAuley, CM, Sonbol, H   +4 more
core   +1 more source

Risk factors for recurrence in patients with Clostridium difficile infection due to 027 and non-027 ribotypes [PDF]

, 2018
Objectives: Our objective was to evaluate factors associated with recurrence in patients with 027+ and 027– Clostridium difficile infection (CDI). Methods: Patients with CDI observed between January and December 2014 in six hospitals were consecutively ...
Aceti, A., Andreoni, M., Antonelli, G., Carfagna, P., Cauda, R., Delle Rose, D., Falcone, M., Fantoni, M., Farcomeni, A., Fontana, C., Goldoni, P., Iraci, F., Mastroianni, C., Murri, R., Petrosillo, N., Raponi, G., Sanguinetti, M., Santino, I., Tiseo, G., Venditti, M.   +19 more
core   +1 more source

Culture of Clinical Specimens Reveals Extensive Diversity of Legionella pneumophila Strains in Arizona

mSphere, 2019
Between 2000 and 2017, a total of 236 Legionella species isolates from Arizona were submitted to the CDC for reference testing. Most of these isolates were recovered from bronchoalveolar lavage specimens.
Brian H. Raphael, Trung Huynh, Ellen Brown, Jessica C. Smith, Irene Ruberto, Linda Getsinger, Stacy White, Jonas M. Winchell   +7 more
doaj   +1 more source

Novel hemotropic mycoplasmas are widespread and genetically diverse in vampire bats [PDF]

, 2017
Bats (Order: Chiroptera) have been widely studied as reservoir hosts for viruses of concern for human and animal health. However, whether bats are equally competent hosts of non-viral pathogens such as bacteria remains an important open question. Here,
Altizer, S.M., Becker, D.J., Bergner, L.M., Camus, M.S., Chizhikov, V.E., Orton, R.J., Streicker, D.G., Volokhov, D.V.   +7 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Laboratory Focus on Improving the Culture of Biosafety: Statewide Risk Assessment of Clinical Laboratories That Process Specimens for Microbiologic Analysis [PDF]

, 2018
The Wisconsin State Laboratory of Hygiene challenged Wisconsin laboratories to examine their biosafety practices and improve their culture of biosafety.
Batemman, Allen C., Beck, eric, Block, Timothy K., Bowles, Erin J., Dern, Richard, Kropp, Joshua L., Munson, Erik, Podzorski, Raymond P., Radke, Tyler, Siebers, Karen, Simmons, Brian, Smith, Mary A., Spray-Larson, Frances, Warshauer, David M.   +13 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Anisakis Allergy: Is Aquacultured Fish a Safe and Alternative Food to Wild-Capture Fisheries for Anisakis simplex-Sensitized Patients?

Biology, 2021
Background: Anisakis simplex (A. simplex) infection, in humans, causes a series of clinical manifestations affecting the gastro-intestinal tract known as Anisakiasis/Anisakidosis.
Lorenzo Polimeno, Maria Teresa Lisanti, Margherita Rossini, Edoardo Giacovazzo, Lucrezia Polimeno, Lucantonio Debellis, Andrea Ballini, Skender Topi, Luigi Santacroce   +8 more
doaj   +1 more source

Cocirculation of Hajj and non-Hajj strains among serogroup W meningococci in Italy, 2000 to 2016 [PDF]

, 2019
In Italy, B and C are the predominant serogroups among meningococci causing invasive diseases. Nevertheless, in the period from 2013 to 2016, an increase in serogroup W Neisseria meningitidis (MenW) was observed.
Arghittu M., Barbui A. M., Bernaschi P., Bisbano A., Chironna M., Ciammaruconi A., De Nittis R., Fazio C., Galanti I. A., Giammanco A., Isola P., Mencacci A., Neri A., Pagani E., Stefanelli P., Vacca P., Vocale C.   +16 more
core   +1 more source