Results 41 to 50 of about 602,240 (294)

Clinical Microbiology in the Year 2025 [PDF]

open access: yesJournal of Clinical Microbiology, 2002
This article offers a mini-preview of what's to come in the field of clinical microbiology, and it's the first such undertaking that any of the authors has ever attempted without tongue firmly planted in cheek. Obviously, the scenario portrayed herein is an exercise in pure fantasy, based loosely on the evolutionary pace of clinical microbiology ...
W Michael, Dunne   +2 more
openaire   +2 more sources

Digital microbiology

open access: yes, 2020
Digitalization and artificial intelligence have an important impact on the way microbiology laboratories will work in the near future. Opportunities and challenges lie ahead to digitalize the microbiological workflows.
Schrenzel, J.   +5 more
core   +1 more source

Current mentorship practices in the training of the next generation of clinical microbiology and infectious disease specialists : an international cross-sectional survey [PDF]

open access: yes, 2019
The purpose of this study was to describe the current practice of mentorship in clinical microbiology (CM) and infectious diseases (ID) training, to identify possible areas for improvement and to assess the factors that are associated with satisfactory ...
Cevik, Muge   +15 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Culture of Clinical Specimens Reveals Extensive Diversity of Legionella pneumophila Strains in Arizona

open access: yesmSphere, 2019
Between 2000 and 2017, a total of 236 Legionella species isolates from Arizona were submitted to the CDC for reference testing. Most of these isolates were recovered from bronchoalveolar lavage specimens.
Brian H. Raphael   +7 more
doaj   +1 more source

The role of microbiology and pharmacy departments in the stewardship of antibiotic prescribing in European hospitals [PDF]

open access: yes, 2007
This observational, cross-sectional study describes the role played by clinical microbiology and pharmacy departments in the stewardship of antibiotic prescribing in European hospitals.
MacKenzie, F.M.   +19 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

High-throughput epidemiologic typing in clinical microbiology

open access: yes, 2003
Mapping, and ultimately preventing, the dissemination of infectious agents is an important topic in public health. Newly developed molecular—microbiological methods have contributed significantly to recent advances in the efficient tracking of the ...
Belkum, A. van, Belkum, Alex
core   +1 more source

The State of Microbiology Diagnostic of Prosthetic Joint Infection in Europe: An In-Depth Survey Among Clinical Microbiologists [PDF]

open access: yes, 2022
BACKGROUND: This study aims to give an overview on how microbiology diagnosis tests of Prosthetic joint infections (PJI) is performed in Europe, and to explore whether any factor influences the decision on implementing a test.
Esteban, Jaime   +6 more
core   +1 more source

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