Results 181 to 190 of about 123,305 (272)

Creativity and its link to epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract Creative thinking represents one of our highest‐order cognitive processes, involving multiple cortical structures and an intricate interplay between several cortical and subcortical networks. It results in novel ideas that translate to useful products or concepts. The evolutionary purpose of creativity is therefore apparent, as it advances our
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

open access: yesEpilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang   +3 more
wiley   +1 more source

Sleep enhances gamma oscillations in the seizure onset zone and broadband activity in the irritative zone of focal cortical dysplasia

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Focal cortical dysplasia (FCD) is a leading cause of drug‐resistant epilepsy and is associated with sleep‐related seizures, yet the underlying electrophysiological mechanisms during different brain states remain poorly understood. We investigated whether fast oscillations (FOs) within the seizure onset zone (SOZ) and irritative zone (
Mohammad F. Khazali   +14 more
wiley   +1 more source

Cognitive safety under epicranial cortex stimulation of the epileptic focus

open access: yesEpilepsia Open, EarlyView.
Abstract Epicranial focal cortex stimulation (FCS) is a new CE‐certified treatment for pharmacoresistant focal epilepsy. In a multicenter observational trial, we report cognitive tolerability in 11 patients with pharmacoresistant epilepsy undergoing epicranial focal cortex stimulation (eFCS) over the predominant seizure focus (left temporal (N = 4 ...
Kathrin Wagner   +10 more
wiley   +1 more source

Efficacy of neurosurgical interventions for epilepsy in polymicrogyria: A systematic review

open access: yesEpilepsia Open, EarlyView.
Abstract Polymicrogyria (PMG) is a rare malformation of cortical development (MCD) characterized by abnormal neuronal architecture, often associated with epilepsy. Neurosurgical interventions have been explored, but their effectiveness remains a subject of ongoing research and debate.
Sergio Rinella   +4 more
wiley   +1 more source

Clinical outcomes and learning curve of MRgLITT system for drug‐resistant epilepsy in China: A single‐center retrospective study

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Magnetic resonance‐guided laser interstitial thermal therapy (MRgLITT) is a minimally invasive technique that allows for real‐time magnetic resonance imaging (MRI) monitoring and precise ablation of epileptogenic lesions. This study reports our initial clinical experience with a domestically developed MRgLITT system in patients with ...
Sichang Chen   +6 more
wiley   +1 more source

Abnormal Forgetting Rate from the Recency Portion of a Word-List in Patients with Subjective Cognitive Decline. [PDF]

open access: yesArch Clin Neuropsychol
Leonardi C   +9 more
europepmc   +1 more source

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