Results 31 to 40 of about 839,620 (307)

The effect of head cooling and remote ischemic conditioning on patients with traumatic brain injury

iScience, 2021
Summary: Cerebral impairment caused by an external force to the head is known as traumatic brain injury (TBI). The aim of this study was to determine the role of local hypothermia and remote ischemic conditioning (RIC) on oxidative stress, inflammatory ...
Fardin Hodoodi, Mohammad Allah-Tavakoli, Farzad Tajik, Iman Fatemi, Amir Moghadam Ahmadi   +4 more
doaj   +1 more source

Free will, neuroscience, and choice: towards a decisional capacity model for insanity defense evaluations [PDF]

, 2017
Il libero arbitrio è stato spesso considerato una tematica centrale nella dottrina della responsabilità criminale. Ciononostante, il concetto stesso di libero arbitrio presenta intrinseche problematiche nella sua definizione teorica e applicazione ...
Biondi, Massimo, Ferracuti, Stefano, Mandarelli, Gabriele, Meynen, Gerben, Parmigiani, Giovanna, Tarsitani, Lorenzo   +5 more
core   +1 more source

Exploring sexual dimorphism in basal forebrain volume changes during aging and neurodegenerative diseases

iScience
Summary: Patients with neurodegenerative diseases exhibit diminished basal forebrain (BF) volume compared to healthy individuals. However, it’s uncertain whether this difference is consistent between sexes.
Yajun Shi, Dong Cui, Fengzhu Sun, Zhen OuYang, Ruhai Dou, Qing Jiao, Weifang Cao, Guanghui Yu   +7 more
doaj   +1 more source

Symbiotic electroneural and musculoskeletal framework to encode proprioception via neurostimulation: ProprioStim

iScience, 2023
Summary: Peripheral nerve stimulation in amputees achieved the restoration of touch, but not proprioception, which is critical in locomotion. A plausible reason is the lack of means to artificially replicate the complex activity of proprioceptors.
Andrea Cimolato, Federico Ciotti, Jelena Kljajić, Giacomo Valle, Stanisa Raspopovic   +4 more
doaj   +1 more source

Contralateral dominance to speech in the adult auditory cortex immediately after cochlear implantation

iScience, 2022
Summary: Sensory deprivation causes structural and functional changes in the human brain. Cochlear implantation delivers immediate reintroduction of auditory sensory information.
Maureen J. Shader, Robert Luke, Colette M. McKay   +2 more
doaj   +1 more source

Neuroenhancement of exposure therapy in anxiety disorders [PDF]

, 2015
Although exposure-based treatments and anxiolytic medications are more effective than placebo for treating anxiety disorders, there is still considerable room for further improvement.
Curtiss, Joshua, Hofmann, Stefan G., Mundy, Elizabeth A.   +2 more
core   +2 more sources

Neuromonitoring-guided working memory intervention in children with ADHD

iScience
Summary: We proposed a personalized intervention that integrates computerized working memory (WM) training with real-time functional neuromonitoring and neurofeedback (NFB) to enhance frontoparietal activity and improve cognitive and clinical outcomes in
Ali Rahimpour Jounghani, Elveda Gozdas, Lauren Dacorro, Bárbara Avelar-Pereira, Samantha Reitmaier, Hannah Fingerhut, David S. Hong, Glen Elliott, Antonio Y. Hardan, Stephen P. Hinshaw, S.M. Hadi Hosseini   +10 more
doaj   +1 more source

Alzheimer's Aβ assembly binds sodium pump and blocks endothelial NOS activity via ROS-PKC pathway in brain vascular endothelial cells

iScience, 2021
Summary: Amyloid β-protein (Aβ) may contribute to worsening of Alzheimer’s disease (AD) through vascular dysfunction, but the molecular mechanism involved is unknown. Using ex vivo blood vessels and primary endothelial cells from human brain microvessels,
Tomoya Sasahara, Kaori Satomura, Mari Tada, Akiyoshi Kakita, Minako Hoshi   +4 more
doaj   +1 more source

Adolescents’ pain-related ontogeny shares a neural basis with adults’ chronic pain in basothalamo-cortical organization

iScience
Summary: During late adolescence, the brain undergoes ontogenic organization altering subcortical-cortical circuitry. This includes regions implicated in pain chronicity, and thus alterations in the adolescent ontogenic organization could predispose to ...
Nils Jannik Heukamp, Tobias Banaschewski, Arun L.W. Bokde, Sylvane Desrivières, Antoine Grigis, Hugh Garavan, Penny Gowland, Andreas Heinz, Mina Kandić, Rüdiger Brühl, Jean-Luc Martinot, Marie-Laure Paillère Martinot, Eric Artiges, Dimitri Papadopoulos Orfanos, Herve Lemaitre, Martin Löffler, Luise Poustka, Sarah Hohmann, Sabina Millenet, Juliane H. Fröhner, Michael N. Smolka, Katrin Usai, Nilakshi Vaidya, Henrik Walter, Robert Whelan, Gunter Schumann, Herta Flor, Frauke Nees   +27 more
doaj   +1 more source

Nicotinamide riboside supplementation is not associated with altered methylation homeostasis in Parkinson’s disease

iScience, 2023
Summary: Replenishing nicotinamide adenine dinucleotide (NAD) via supplementation of nicotinamide riboside (NR) has been shown to confer neuroprotective effects in models of aging and neurodegenerative diseases, including Parkinson’s disease (PD ...
Johannes J. Gaare, Christian Dölle, Brage Brakedal, Kim Brügger, Kristoffer Haugarvoll, Gonzalo S. Nido, Charalampos Tzoulis   +6 more
doaj   +1 more source