Results 31 to 40 of about 80,892 (260)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Enlightenment of American clinical nursing post and nurse category to development direction of nursing specialty in China

Huli yanjiu, 2020
The paper introduced the duties of nurse assistant， professional operating nurses，registered nurses，practicing nurses，travel nurses and specialist nurse in the USA.It was showed that diverse clinical nursing post，specific division of responsibilities ...
XUE Xiaojing, YANG Xiaolin, Ka Yee Chan, HE Fang   +3 more
doaj  

Attitudes of Parents Living in Rural and Urban Areas in Kütahya Province Towards Childhood Vaccines

Mediterranean Nursing and Midwifery, 2023
Objective:The aim of the study was to investigate the attitudes of parents living in rural and urban areas towards childhood vaccinations using the health belief model.Method:The study is of descriptive comparative research type.
Nalan Bostan Akmeşe, Buşra Arık
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Increasing research capacity in an academically isolated mental health trust

BJPsych Bulletin
Aims and method Involvement in clinical mental health research can be a challenge for services isolated from academic institutions, limiting opportunities for patients to receive innovative interventions and for clinicians to explore interest in ...
Adrian J. Hayes, Alicia Long, Carinna Vickers   +2 more
doaj   +1 more source

Current status of clinical nursing specialists and the demands of osteoporosis specialized nurses in Mainland China

International Journal of Nursing Sciences, 2014
The clinical nursing specialist (CNS) is an expert who applies an expanded range of practical, theoretical, and research-based competencies to the care of patients within in a specialty clinical area within the larger discipline of nursing.
Xu Tian, Jun-xiao Lian, Li-juan Yi, Li Ma, Yan Wang, Hong Cao, Guo-min Song   +6 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Medical staff's cognition and experience of specialist nurse practice in critical care unit: a qualitative study

Frontiers in Health Services
BackgroundSpecialist nurses represent an important pathway through which registered nurses transition toward advanced practice nurse roles, and their development and clinical practice are essential for addressing contemporary healthcare challenges ...
MengJuan Jing, XiaoJing Wei, ChunPeng Li, YuLin Xu, LiMing Li, Hao Li   +5 more
doaj   +1 more source

Growing up with confidence: using telehealth to support continence self-care deficits amongst young people with complex needs

Journal of Innovation in Health Informatics, 2014
Background Many young people with chronic ill health use technology for selfcare activities, but little is known about the use of telehealth amongst those with spina bifida.
Sharon Levy, Lisa Henderson, Caroline McAlpine   +2 more
doaj   +1 more source