Results 111 to 120 of about 5,379,197 (286)

The evaluation of clinical outcomes assessments and digital health technologies in clinical trials for obesity

Journal of Patient-Reported Outcomes
Background Clinical trials for obesity have traditionally focused on weight loss and resolution of comorbidities as primary outcomes. However, secondary outcomes, such as the impact of weight reduction on patient experience, like health-related quality ...
Iris A. Goetz, Carolyn Sutter, Traci Abraham, Chisom Kanu, Kristina S. Boye, Tara Symonds   +5 more
doaj   +1 more source

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou, Konstantina Dipla, Danai Faitatzidou, Fotini Iatridi, Areti Georgiou, Artemios Karagiannidis, Erasmia Sampani, Chrysostomos Dimitriadis, Aggelos Koutlas, Andreas Zafeiridis, Pantelis Sarafidis   +10 more
wiley   +1 more source

Intraoperative Collection of Ascitic Fluid With Intra‐ or Postoperative Reinfusion in Ovarian Cancer: Safety and Feasibility of a Roller Pumping Method

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients with ovarian cancer often present with massive ascites, leading to significant protein loss during surgical procedures. Although cell‐free concentrated ascites reinfusion therapy (CART) is used in palliative settings to mitigate protein loss, its application in intraoperative settings remains unexplored.
Yutaka Yoneoka, Tsukuru Amano, Akimasa Takahashi, Mari Deguchi, Hiroyuki Yamanaka, Yuji Tanaka, Shunichiro Tsuji, Takashi Murakami   +7 more
wiley   +1 more source

CLINICAL OUTCOMES [PDF]

Japanese Journal of Clinical Oncology, 2011
Y. Horikawa, N. Tsuchiya, K. Yuasa, S. Narita, M. Saito, K. Takayama, T. Nara, H. Tsuruta, T. Obara, K. Numakura, S. Satoh, T. Habuchi, X. Hu, J. Guo, Z. Lin, L. Sun, Z. Xu, C. Cang, G. Wang, T. Kanda, K. Sakamoto, A. Matsuki, R. Ohashi, S. Hirota, Y. Fujimori, Y. Matsuda, K. Yajima, S. Kosugi, K. Hatakeyama, K. Kitahara, M. Watanabe, S. Nakazono, N. Wada, H. Kakizaki, J. Li, F. J. Gong, P. N. Sun, L. Shen, Q. Li, N. Li, M. Qiu, J. Liu, C. Yi, D. Luo, Z. Li, H. Gou, Y. Yang, D. Cao, Y. Shen, X. Wang, F. Xu, F. Bi, Q. Li, X. Zhang, N. Li, W. Wei, H. Y. Luo, Z. Q. Wang, F. H. Wang, M. Z. Qiu, K. Y. Teng, D. Y. Ruan, Y. J. He, Y. H. Li, R. H. Xu, S. Matsusaka, N. Mizunuma, M. Suenaga, E. Shinozaki, Y. Mishima, Y. Terui, K. Hatake, E. Nara, M. Kodaira, Y. Mishima, M. Yokoyama, T. Saotome, Y. Terui, S. Takahashi, K. Hatake, N. Nishimura, K. Nakano, M. Kodaira, K. Ueda, S. Yamada, Y. Mishima, M. Yokoyama, T. Saotome, S. Takahashi, Y. Terui, K. Hatake, M. Nozawa, Y. Mochida, K. Nishigaki, S. Nagae, H. Uemura, S. Y. Oh, C. Y. Jeong, S. C. Hong, W. S. Lee, H. G. Kim, G.-W. Lee, I. G. Hwang, J. S. Jang, H.-C. Kwon, J. H. Kang, M. Ozaka, M. Ogura, S. Matsusaka, E. Shinozaki, M. Suenaga, K. Chin, N. Mizunuma, K. Hatake, P. F. Pua, D. Ganzon, V. Chan, K. Sailaja, S. Vishnupriya, D. Raghunadharao, G. Markandeya, P. R. K. Reddy, P. Reddanna, D. Praveen, K. Sakamoto, T. Kanda, A. Matsuki, T. Takano, T. Hanyu, K. Yajima, S. Kosugi, S. Hirota, K. Hatakeyama, T. Shigekawa, N. Ijichi, S. Takayama, H. Tsuda, K. Ikeda, K. Horie, A. Osaki, T. Saeki, S. Inoue, J. Subhashini, B. Rajesh, I. Rajesh, P. Ravindran, K. Takagi, K. Chin, M. Oba, Y. Kuboki, T. Ichimura, M. Oto, Y. Kawazoe, T. Watanabe, M. Ozaka, M. Ogura, M. Suenaga, E. Shinozaki, S. Matsusaka, N. Mizunuma, K. Hatake, K. Ueda, T. Saotome, S. Yamada, N. Nishimura, E. Nara, K. Nakano, M. Kodaira, A. Katsube, Y. Mishima, Y. Terui, M. Yokoyama, S. Takahashi, K. Hatake, X. Yao, Q. Yang, C. Li, L. Diao, X. Chen, Z. Yu, W. Zuo, Y. Wang, Y. He, X. Zhang, S. Cai, Z. Wang, J. Xu, W. Zhan, Y. F. Zhang, M. Misumi, H. Takeuchi, N. Nakamiya, T. Shigekawa, K. Matsuura, N. Fujiuchi, A. Osaki, T. Saeki   +196 more
openaire   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Liquid Hydroxyurea (Xromi) for Children With Sickle Cell Anemia: A New Solution Compounding Existing Problems

Pediatric Blood &Cancer, EarlyView.
Alexandra Power‐Hays, Charles T. Quinn
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Developing a Process for Preference Measures in Pediatric Growth Hormone Deficiency: Challenges and Solutions

Patient Preference and Adherence
Meryl Brod,1 Kathryn M Pfeiffer,1 Suzanne Lessard Alolga,1 Jane F Beck,1 Morgan Murphy,2 Aleksandra K Bruchey,3 Aristides Maniatis,4 Pisit Pitukcheewanont5 1Health Outcomes Research, The Brod Group, Mill Valley, CA, USA; 2Research & Development ...
Brod M, Pfeiffer KM, Alolga SL, Beck JF, Murphy M, Bruchey AK, Maniatis A, Pitukcheewanont P   +7 more
doaj  

Snapshot: Trial Types in Precision Medicine. [PDF]

, 2020
Integrating precision diagnostics into personalized treatments requires understanding how biomarkers relate to clinical outcomes. Various clinical data collection methods exist, each with strengths and weaknesses. Interventional data are high quality but
Bergan, Raymond, Dickson, Dane, Johnson, Jennifer, Kurzrock, Razelle, Owens, Rebecca, Subbiah, Vivek   +5 more
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