Results 11 to 20 of about 11,110,115 (247)

The impact of pharmacokinetic-guided prophylaxis on clinical outcomes and healthcare resource utilization in Hemophilia A patients: Real-world evidence from the CHESS II study [PDF]

, 2022
Background: Using a pharmacokinetic (PK)-guided approach to personalize the dose and frequency of prophylactic treatment can help achieve and maintain targeted factor VIII (FVIII) trough levels in patients with hemophilia A.
O'Hara, Jamie, Ferri Grazzi, Enrico, Sun, Shawn X, Burke, Tom, Sun, Shawn X., O’Hara, Jamie   +5 more
core   +1 more source

Medication Use and Clinical Outcomes by the Dutch Institute for Clinical Auditing Medicines Program: Quantitative Analysis [PDF]

, 2022
BACKGROUND: The Dutch Institute for Clinical Auditing (DICA) Medicines Program was set up in September 2018 to evaluate expensive medicine use in daily practice in terms of real-world effectiveness using only existing data sources.
van Breeschoten, Jesper, Hilarius, Doranne, Pasmooij, Anna Maria Gerdina, van Loosen, Caspar, van Dartel, Maaike, de Boer, Anthonius, Wouters, Michel, Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Ismail, Rawa Kamaran, van der Flier, Silvia, van den Eertwegh, Alfons   +11 more
core   +2 more sources

Impact of clinical supervision on healthcare organisational outcomes: A mixed methods systematic review [PDF]

, 2021
Objective To review the impact of clinical supervision of post-registration/qualification healthcare professionals on healthcare organisational outcomes.
Lizarondo, Lucylynn, Snowdon, David, Martin, Priya, Kumar, Saravana   +3 more
core   +1 more source

A novel patient-reported outcome instrument assessing the symptoms of paroxysmal nocturnal hemoglobinuria, the PNH-SQ

Journal of Patient-Reported Outcomes, 2021
Background Patient-reported outcome measures (PROs) used to measure symptoms of patients with paroxysmal nocturnal hemoglobinuria (PNH) in trials do not measure PNH symptoms comprehensively and do not assess daily fluctuations in symptoms.
R. Paola Daly, Jessica J. Jalbert, Shannon Keith, Tara Symonds, Jamile Shammo   +4 more
doaj   +1 more source

Statistical analysis of the primary outcome in acute stroke trials [PDF]

, 2012
Common outcome scales in acute stroke trials are ordered categorical or pseudocontinuous in structure but most have been analyzed as binary measures. The use of fixed dichotomous analysis of ordered categorical outcomes after stroke (such as the modified
Lees, K.R., Saver, J.L., Howard, G., TONI, Danilo, Altman, H., Schellinger, P.D., Bland, M., Hogg, C., Bath, P.M.W., European Stroke Organisation Outcomes Working Group   +9 more
core   +1 more source

Practice Patterns and Training Needs Among Physicians Certifying Patients for Medical Marijuana in Florida

Journal of Primary Care & Community Health, 2021
Background: Little is known about the clinical training or practice experiences among physicians who certify patients for medical marijuana. The objective of this study was to determine information sources, factors influencing recommendations, clinical ...
Ruba Sajdeya, Anna Shavers, Jennifer Jean-Jacques, Brianna Costales, Sebastian Jugl, Carly Crump, Yan Wang, Luran Manfio, R. Nathan Pipitone, Martha S. Rosenthal, Almut G. Winterstein, Robert L. Cook   +11 more
doaj   +1 more source

Dispensing of antibiotics without prescription in the metropolitan area of Athens, Greece, in 2021—Can new legislation change old habits?

Antimicrobial Stewardship & Healthcare Epidemiology, 2023
Objective: To assess the effect of new legislation on the dispensing of antimicrobials without prescription from pharmacies in Greece. Design: In-person survey.
Ioannis Kopsidas, Lydia Kokkinidou, Dioni Pinelopi Petsiou, Eleni Kourkouni, Christos Triantafyllou, Grammatiki-Christina Tsopela, Theoklis Zaoutis   +6 more
doaj   +1 more source

Comparability of a provisioned device versus bring your own device for completion of patient-reported outcome measures by participants with chronic obstructive pulmonary disease: quantitative study findings

Journal of Patient-Reported Outcomes, 2022
Highlights Historically, provisioned handheld devices [PD] have been provided to participants to enter patient-reported outcome (PRO) data during a clinical trial.
Stacie Hudgens, Louise Newton, Sonya Eremenco, Mabel Crescioni, Tara Symonds, Philip C. G. Griffiths, David S. Reasner, Bill Byrom, Paul O’Donohoe, Susan Vallow, the Patient-Reported Outcome (PRO) Consortium and Electronic Clinical Outcome Assessment (eCOA) Consortium   +10 more
doaj   +1 more source

Factor analysis of treatment outcomes from a UK specialist addiction service:relationship between the Leeds Dependence Questionnaire, Social Satisfaction Questionnaire and 10-item Clinical Outcomes in Routine Evaluation [PDF]

, 2014
To examine the relationship between three outcome measures used by a specialist addiction service (UK): the Leeds Dependence Questionnaire (LDQ), the Social Satisfaction Questionnaire (SSQ) and the 10-item Clinical Outcomes in Routine Evaluation (CORE-10)
Fairhurst, Caroline, Raistrick, Duncan, Gillian Tober, Gabe, Rhian, Tober, Gillian, Tim J. Croudace, Jan R. Böhnke, Rhian Gabe, Croudace, Tim J.; id_orcid, Caroline Fairhurst, Böhnke, Jan R.; id_orcid, Duncan Raistrick   +11 more
core   +1 more source

Impacts and Burden of Niemann pick Type-C: a patient and caregiver perspective

Orphanet Journal of Rare Diseases, 2021
Background Niemann-Pick disease type C (NPC) is a debilitating condition that impacts patients’ and caregivers’ quality of life (QOL) and reduces the patient’s life expectancy.
Eugen Mengel, Marc C. Patterson, Michael Chladek, Christina Guldberg, Christine í Dali, Tara Symonds, Lucy Lloyd-Price, Toni Mathieson, Joslyn Crowe, Claire Burbridge   +9 more
doaj   +1 more source