Results 21 to 30 of about 5,538,732 (291)

Stem Cell Transplantation As A Dynamical System: Are Clinical Outcomes Deterministic? [PDF]

, 2014
Outcomes in stem cell transplantation (SCT) are modeled using probability theory. However the clinical course following SCT appears to demonstrate many characteristics of dynamical systems, especially when outcomes are considered in the context of immune
Buck, Gregory A, Chung, Harold, Clark, William, Jameson-Lee, Max, Kobulnicky, Jared D, Koparde, Vishal, Manjili, Masoud H, McCarty, John, Meier, Jeremy, Neale, Michael C, Roberts, Catherine H, Sabo, Roy T, Salman, Salman, Scalora, Allison, Serrano, Myrna, Sheth, Nihar, Toor, Amir A   +16 more
core   +3 more sources

Epidemiology and clinical outcomes [PDF]

European Heart Journal, 2015
Download the Issue @ a Glance podcast Subscribe to the EHJ Podcast ![Graphic][1] Epidemiology has revealed important differences in the onset and frequency of cardiovascular risk factors and disease among males and females. Both the presentation of symptoms and the natural course may differ among men and women, for instance in coronary disease1–3 ...
openaire   +3 more sources

Study protocol for the Anesthesiology Control Tower—Feedback Alerts to Supplement Treatments (ACTFAST-3) trial: A pilot randomized controlled trial in intraoperative telemedicine [version 1; referees: 2 approved] [PDF]

, 2018
Background: Each year, over 300 million people undergo surgical procedures worldwide. Despite efforts to improve outcomes, postoperative morbidity and mortality are common.
ACTFAST Study Group,, Avidan, Michael S, Ben Abdallah, Arbi, Fritz, Bradley A, Gregory, Stephen, Helsten, Daniel L, Murray-Torres, Teresa M, Sharma, Anshuman, Wildes, Troy S   +8 more
core   +2 more sources

Burden of illness of trigeminal neuralgia among patients managed in a specialist center in England

The Journal of Headache and Pain, 2020
Background Trigeminal neuralgia (TN) causes severe episodic, unilateral facial pain and is initially treated with antiepileptic medications. For patients not responding or intolerant to medications, surgery is an option.
Lasair O’Callaghan, Lysbeth Floden, Lisa Vinikoor-Imler, Tara Symonds, Kathryn Giblin, Chris Hartford, Joanna M. Zakrzewska   +6 more
doaj   +1 more source

Developing Angelman syndrome-specific clinician-reported and caregiver-reported measures to support holistic, patient-centered drug development

Orphanet Journal of Rare Diseases, 2023
Background Angelman syndrome (AS) is a rare, heterogenous neurogenetic condition, which significantly impacts the lives of people with AS and their families. Valid and reliable measures reporting key symptoms and functional impairments of AS are required
Siobhan Connor-Ahmad, Jorrit Tjeertes, Michael Chladek, Louise Newton, Tara Symonds, Susanne Clinch, Brenda Vincenzi, Fiona McDougall   +7 more
doaj   +1 more source

Clinical Characteristics and Outcomes Among Individuals With Spinal Implant Infections: A Descriptive Study. [PDF]

, 2016
Little is known about the clinical presentation and outcomes associated with spinal implant infections. Here, we describe a single center's experience in a retrospective cohort of 109 individuals with spinal implant infections, including clinical ...
Baxi, Sanjiv M, Doernberg, Sarah B, Grill, Marie F, Liu, Catherine, Robinson, Makeda L, Schwartz, Brian S   +5 more
core   +1 more source

Comparability of a provisioned device versus bring your own device for completion of patient-reported outcome measures by participants with chronic obstructive pulmonary disease: qualitative interview findings

Journal of Patient-Reported Outcomes, 2022
Background There is interest in participants using their own smartphones or tablets (“bring your own device”; BYOD) to complete patient-reported outcome (PRO) measures in clinical studies.
Louise Newton, Oliver Knight-West, Sonya Eremenco, Stacie Hudgens, Mabel Crescioni, Tara Symonds, David S. Reasner, Bill Byrom, Paul O’Donohoe, Susan Vallow, the Patient-Reported Outcome (PRO) Consortium, Electronic Clinical Outcome Assessment (eCOA) Consortium   +11 more
doaj   +1 more source

Proceedings of the 2022 Cannabis Clinical Outcomes Research Conference

Medical Cannabis and Cannabinoids, 2022
The Consortium for Medical Marijuana Clinical Outcomes Research, a multi-university collaboration established by the state of Florida in the USA, hosted its second annual Cannabis Clinical Outcomes Research Conference (CCORC) in May 2022.
Nicole E. Smolinski, Ruba Sajdeya, Robert Cook, Yan Wang, Almut G. Winterstein, Amie Goodin   +5 more
doaj   +1 more source

Patient‐Reported Outcome Measures for Severe Recurrent Bilateral Nasal Polyps: Psychometric Evaluation and Content Validity

OTO Open, 2023
Objective To date, no patient‐reported outcome measures have been specifically developed to assess pharmacological treatment effect in participants with severe chronic rhinosinusitis (CRS) with recurrent bilateral nasal polyps (NP).
Adam Gater, Chloe Tolley, Rebecca Williams‐Hall, Claire Trennery, Helena Bradley, Mirko V. Sikirica, Linda Nelsen, Ana R. Sousa, Daniel J. Bratton, Robert Chan, Robyn vonMaltzahn   +10 more
doaj   +1 more source

Is the relationship among outcome variables shown in randomized trials? [PDF]

, 2015
BACKGROUND: Randomized controlled trials (RCTs) often have more than one primary outcome and frequently have secondary and harm outcomes. Comparison of outcomes between study arms is the primary focus of RCTs, but there are times when the relation ...
Altman, Douglas, Cooper, Richelle, Lopez-OSullivan, Ana, Schriger, David, Wystrach, Carter   +4 more
core   +1 more source