Results 171 to 180 of about 8,138,914 (303)

Integrating Patient-Reported Outcomes into Clinical Pathways in Atrial Fibrillation: A Framework Aligned with the AF-CARE Model. [PDF]

Diagnostics (Basel)
Sokolova E, Goetz O, Grīnberga K, Sen SE, Kupics K, Mača-Kalēja A, Rudzītis A, Behmane D, Kalējs O.   +8 more
europepmc   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Exploring Acute Pancreatitis Clinical Pathways Using a Novel Process Mining Method. [PDF]

Healthcare (Basel), 2023
Yang X, Huang W, Zhao W, Zhou X, Shi N, Xia Q.   +5 more
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Evolution of the prostate cancer diagnostic paradigm: integrated evidence and clinical pathways from targeted biopsy to biopsy-free strategy. [PDF]

Front Oncol
Liu Z, Wu J, Lu Q, Li Y, Yang Y.
europepmc   +1 more source

Clinical Pathway Management of Tonsillectomy

Practica oto-rhino-laryngologica. Suppl., 2015
Ida, Yutaro, Osafune, Hiroshi, Matsushima, Koji, Edamatsu, Hideo   +3 more
openaire   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Diagnostic Documentation and Tumour Marker Availability Across Clinical Pathways in Real-World Gastric Cancer. [PDF]

Diagnostics (Basel)
Vieru AM, Rădulescu VM, Mustață ML, Trașcă E, Cazacu SM, Popa P, Ciurea T.   +6 more
europepmc   +1 more source

Socioeconomic Predictors of Crisis and Clinical Pathways Among People Contacting a Mental Health Crisis Line. [PDF]

Health Serv Insights, 2023
McCarthy M, McIntyre JC, Nathan R, Ashworth EL, Saini P.   +4 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source