Results 161 to 170 of about 8,138,914 (303)

Development of Clinical Pathways for Early Diagnosis and Management of SCID, SMA, and XLA Through Newborn Screening in Malaysia. [PDF]

Int J Neonatal Screen
Zainudin A, Aye TT, Yun CCS, Kumarasamy G, Ali A.   +4 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Proyecto de mejora de la asistencia sanitaria (MAS): estudio multicéntrico y multidisciplinar. Primeras conclusiones

Medicina y Seguridad del Trabajo
Definir el método de trabajo utilizado en el estudio de la Calidad Asistencial de accidentes de trabajo leves, siguiendo las fases del proceso (estudio del proceso desde su entrada en admisión, la historia clínica, la comunicación entre servicios ...
Carolina Gerónimo Blasco, Eduardo Viver Bernadó, María del Mar Blázquez Sánchez, Joaquín Verdugo López, Manuel Mendoza López   +4 more
doaj  

Extracorporeal Membrane Oxygenation in Refractory Cardiac Arrest: Current Evidence, Clinical Pathways and Future Directions. [PDF]

Life (Basel)
Torre DE, Mangino D, Pirri C.
europepmc   +1 more source

Clinical Pathway [PDF]

, 2020
openaire   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Enhancing specialist competence in clinical pathways for left ventricular hypertrophy: design and evaluation of a competency-based curriculum. [PDF]

BMC Health Serv Res
Chen Y, Jiang J, Jin W.
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Precision medicine decision-making under pharmacogenomics in nursing: realizing value from limited evidence to scaled clinical pathways. [PDF]

Front Neurol
Qin G, Luo X, Hao X, Xiao H, Wang K, Pang H, Li M, Pi C, Yang S, Zhang Q.   +9 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source