Results 181 to 190 of about 1,543,622 (248)

A standardised pre-clinical in-vitro blood-brain barrier mouse assay validates endocytosis dependent antibody transcytosis using transferrin receptor-mediated pathways

, 2022
Jamie I. Morrison, Alex Petrovic, Nicole G. Metzendorf, Fadi Rofo, Canan Uğur Yılmaz, Sofia Stenler, Hanna Laudon, Greta Hultqvist   +7 more
openalex   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Predicting clinical pathways of traumatic brain injuries (TBIs) through process mining. [PDF]

NPJ Digit Med
Eili MY, Rezaeenour J, Roozbahani MH.
europepmc   +1 more source

Association of Patient, Physician, and Practice-Level Factors with Uptake of Payer-Led Oncology Clinical Pathways.

JAMA Netw Open, 2023
Mullangi S, Chen X, Pham T, Liu Y, Gordon AS, Debono D, Fisch MJ, Gönen M, Hershman DL.   +8 more
europepmc   +1 more source

Elements Characterising Multicomponent Interventions Used to Improve Disease Management Models and Clinical Pathways in Acute and Chronic Heart Failure: A Scoping Review. [PDF]

Healthcare (Basel), 2023
Pedroni C, Djuric O, Bassi MC, Mione L, Caleffi D, Testa G, Prandi C, Navazio A, Giorgi Rossi P.   +8 more
europepmc   +1 more source

[Correlation analysis of cell-free DNA in gingival crevicular fluid with periodontal clinical indicators and cyclic guanosine phosphate-adenosine phosphate synthase-stimulator of interferon genes signaling pathway].

Lan Chen, Xuanzhi Zhu, Jieyu Zhou, Jiyao Li, Леи Жао   +4 more
openalex   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Primary Central Nervous System Tumors in Adolescents: A Population-Based Study on Epidemiology and Clinical Pathways in a Challenging Age Group. [PDF]

Curr Oncol
De Martino L, Piga P, Sessa M, Calì C, Russo C, Picariello S, Onorini N, Spennato P, Quaglietta L, Donofrio MV, Cinalli G, Vetrano F, Savoia F.   +12 more
europepmc   +1 more source

Towards a clinical pathway to food for special medical purpose in China: current progress based on a cross-sectional survey [PDF]

Jie Gong, Mengyan Wang, Jiankui Guo, Yong Lyu, Dongyu Mu, Lei Shi, Wen Hu, Fengmei Yu   +7 more
openalex   +1 more source