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ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
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Defining clinical outcome pathways
Drug Discovery Today, 2022Here, we propose a broad concept of 'Clinical Outcome Pathways' (COPs), which are defined as a series of key molecular and cellular events that underlie therapeutic effects of drug molecules. We formalize COPs as a chain of the following events: molecular initiating event (MIE) → intermediate event(s) → clinical outcome.
Daniel, Korn +14 more
openaire +2 more sources
Nursing Management, 2011
The National Institute for Health and Clinical Excellence (NICE) has launched an online tool that brings together its guidance and products in a set of interactive topic-based diagrams.
openaire +2 more sources
The National Institute for Health and Clinical Excellence (NICE) has launched an online tool that brings together its guidance and products in a set of interactive topic-based diagrams.
openaire +2 more sources
Nutrition Support Clinical Pathways
Nutrition in Clinical Practice, 1996With growing concerns over cost containment, hospitals are using clinical pathways to standardize health care and reduce costs. Clinical pathways designate the actions and services that patients should receive at specified time intervals throughout the hospital stay.
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Introduction to Clinical Pathways
Journal For Healthcare Quality, 1995A clinical pathway is a comprehensive method of planning, delivering, and monitoring patient care. As efforts continue to streamline the delivery of services at all levels of care and settings, it is essential that quality management and utilization management professionals respond in a proactive manner to facilitate quality outcomes while decreasing ...
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