Results 81 to 90 of about 8,138,914 (303)

A liability checklist for clinical pathways

open access: yesNursing Management (Springhouse), 2002
To ensure safe, responsible use of clinical pathways, follow written policies and procedures and document all patient care.
openaire   +3 more sources

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Computerisation of Clinical Pathways

open access: yes, 2017
Patient safety incidents are becoming more common in medical situations. The challenge of achieving significant improvements in patient safety is one of the key tasks facing healthcare at the start of the 21st century.
Jasmine Tehrani
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Diagnosis and staging of patients with ovarian cancer: National Clinical Guideline No. 20 Annex 1: Systematic review of cost effectiveness

open access: yes, 2018
The purpose of this systematic review was to identify and evaluate economic evidence to inform the clinical recommendations of this NCG. Review of the cost-effectiveness of health technologies enables guideline developers to explicitly consider how ...
HRB-CICER (Collaboration in Ireland for Clinical Effectiveness Reviews)
core  

Clinical pathways for chronic cough in children

open access: yes, 2014
Free to read\ud \ud Background\ud \ud Chronic cough (a cough lasting longer than four weeks) is a common problem internationally. Chronic cough has associated economic costs and is distressing to the child and to parents; ignoring cough may lead to ...
Morris, Peter S.   +6 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Advocating for an integrated healthcare model for women of reproductive age in low- and middle-income countries

open access: yesCritical Public Health
Increasingly, women are presenting in pregnancy with multi-risk and multi-morbidity profiles (combinations of pro-inflammatory diets, trauma, anxiety, depression, infections, metabolic disease, and chronic medication use); together these may ...
Lauren Stuart   +3 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Young women’s social support networks during pregnancy in Soweto, South Africa

open access: yesAfrican Journal of Primary Health Care & Family Medicine
Background: Although studies from high-income countries have examined social support during pregnancy, it remains unclear what type of support is received by expectant mothers from low- and middle-income country settings.
Khuthala Mabetha   +6 more
doaj   +1 more source

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