Results 71 to 80 of about 1,672,515 (266)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The Effect of Coordinating the Outpatient Treatment across Medical Specialities for Patients With Multimorbidity

International Journal of Integrated Care
Introduction: Patients with multimorbidity attend multiple outpatient clinics. We assessed the effects on hospital use of scheduling several outpatient appointments to same-day visits in a multidisciplinary outpatient pathway (MOP).
Cathrine Bell, Charlotte Weiling Appel, Anders Prior, Anne Frølich, Asger Roer Pedersen, Peter Vedsted   +5 more
doaj   +1 more source

Pharmacists as Interprofessional Collaborators and Leaders through Clinical Pathways

Pharmacy, 2018
Pharmacists possess pivotal competencies and expertise in developing clinical pathways (CPs). We present a tertiary care facility experience of pharmacists vis-a-vis interprofessional collaboration for designing and implementing CPs.
Sherine Ismail, Mohamed Osman, Rayf Abulezz, Hani Alhamdan, K. H. Mujtaba Quadri   +4 more
doaj   +1 more source

A liability checklist for clinical pathways

Nursing Management (Springhouse), 2002
To ensure safe, responsible use of clinical pathways, follow written policies and procedures and document all patient care.
openaire   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Child Amputee Prosthetics Project—Prosthesis Satisfaction Inventory (CAPP-PSI): Validation of Italian Version in Children with Upper Limb Amputation

Children
Background: The Child Amputee Prosthetics Project—Prosthesis Satisfaction Inventory (CAPP-PSI) is a comprehensive instrument designed to measure satisfaction across functionality, aesthetic, and service domains.
Luigino Santecchia, Gessica Della Bella, Francesca Caspi, Paola Luttazi, Lorenzo Pochiero, Fabrizio Taffoni, Giordana Mariani, Marco Gaudenzi, Donatella Valente, Marco Tofani   +9 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Exodontic surgery in patients with coagulation disorders: a literature review

Annali di Stomatologia
BACKGROUND: Nowadays, patients with coagulation disorders, whether inherited or acquired, have grown significantly. Anticoagulant drugs (vitamin K antagonists, VKA, and the new oral anticoagulants, NAO) and Antiplatelet drugs are a powerful means for ...
Mirko Martelli, Pasquale Giallaurito, Alessandro D’Aurelio, Francesco Gianfreda, Marco Gargari, Patrizio Bollero, Alberta Barlattani, Liliana Ottria   +7 more
doaj   +1 more source

The Economic Rationale for Healthcare Reform [PDF]

International Journal of Health Policy and Management
Healthcare reform is analyzed from an economic perspective. First, the economic rationale for providing access to healthcare lies in the benefit from knowing that those without means would be able to access health services. However, this does not explain
Naoki Ikegami
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source