Results 111 to 120 of about 914,658 (345)

Can student mental health nurses be prepared for medicines management? [PDF]

open access: yes, 2014
Aim This paper reports on an evaluation of the Medicines with Respect project, which implemented a stepped approach to education and training in medicines management (MM) for mental health nurses (MHNs). Method In the retrospective qualitative study,
Hemingway S   +4 more
core   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga   +2 more
wiley   +1 more source

Integrating Family Medicine and Pharmacology: A Holistic Approach to Modern Medical Science – An Expert Opinion

open access: yesJournal of Integrated Health Sciences
The convergence of family medicine and clinical pharmacology signifies a vital evolution in modern healthcare, particularly in the era of chronic diseases, polypharmacy, and rising healthcare expenditures.
SK Sabir Rahaman
doaj   +1 more source

Clinical Pharmacology in the UK, c.1950-2000: Influences and Institutions [PDF]

open access: yes, 2008
Annotated and edited transcript of a Witness Seminar held on 6 February 2007. Introduction by Dr Mark Walport, The Wellcome Trust.First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2008.©The Trustee of the Wellcome Trust ...
Reynolds, LA, Tansey, EM
core  

Experimental pharmacological research regarding some newly synthesized benzamides on central nervous system functions [PDF]

open access: yes, 2017
Three newly synthesized benzamides by the Department of Pharmaceutical Chemistry of the Faculty of pharmacy from the University of Medicine and Pharmacy „Carol Davila” Bucharest were tested in order to determine whether these new molecules have similar ...
Chiriță, Cornel   +4 more
core   +4 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Polypharmacotherapy in Institutionalized Epileptic Children

open access: yesPediatric Neurology Briefs, 1991
An attempt to minimize polypharmacotherapy, to discontinue the use of phenobarbital, and to assess the relation between drug levels and antiepileptic effect in institutionalized severely retarded children is reported from the Department of Pediatrics, St.
J Gordon Millichap
doaj   +1 more source

Subsidized pharmacological treatment for smoking cessationby the Spanish public health system: A randomized, pragmatic,clinical trial by clusters [PDF]

open access: gold, 2019
César Minué-Lorenzo   +9 more
openalex   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

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