Results 121 to 130 of about 468,836 (265)

Clinical Pharmacology Quality Assurance Program for Global HIV and Co-Infection Drug Development. [PDF]

Clin Pharmacol Ther
DiFrancesco R, Wood TD, Cha R, Hochreiter JS, Rosenkranz SL, Farhad M, Whitson KR, Gould CE, Hill LE, Hale LL, Lindhorst PH, Ghazal D, Taylor CR, Quraishi M, Siminski SM, Cramer Y, Sprenger HL, Morse GD.   +17 more
europepmc   +1 more source

Clinical Pharmacology in Practice

Journal of the Royal College of Physicians of London, 1984
R M, Pearson, J C, Mucklow
openaire   +2 more sources

Integration of Serum Neurofilament Light Chain and Cortical Dysfunction Improves Diagnostic Accuracy in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma, Nathan Pavey, Yukiko Tsuji, Amirul Ab Ghapar, Mehdi A.J. van den Bos, Bronwen Orden, Grace Lee, Linda Mekhael, Julie Ryder, Cláudia Santos Silva, David McDonald, Fakhria Kakar, Con Yiannikas, Matthew C. Kiernan, David A. Brown, Parvathi Menon, Steve Vucic   +16 more
wiley   +1 more source

Application of the artificial intelligence-assisted World Café teaching model in clinical pharmacology graduate course: a pilot study. [PDF]

Front Public Health
Guo Y, Zhang LC, Li Q, Xiong YX, Hu WY, Luo HY, Xie JP, Yu HF.   +7 more
europepmc   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Cannabidiol in autism: Clinical pharmacology priorities for trial design. [PDF]

Br J Clin Pharmacol
Aragão GF, Brandão CB, Júnior JEL.
europepmc   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias, Federica Avantaggiato, Gianni Pezzoli, Andrea Canessa   +3 more
wiley   +1 more source

Clinical pharmacology consultations and their implementation in clinical decision making. [PDF]

Br J Clin Pharmacol
Kauppila M, Backman JT, Lapatto-Reiniluoto O.   +2 more
europepmc   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Cardiovascular-Kidney-Metabolic Syndrome in People With HIV: An Emerging Frontier for Clinical Pharmacology. [PDF]

Clin Pharmacol Ther
Devanathan AS, Nolin TD.
europepmc   +1 more source