Results 121 to 130 of about 857,003 (376)

Identifying Drug Prescription in Newly Diagnosed Hypertension Patients in India

open access: yesThe Journal of Clinical Hypertension
This study evaluated initial antihypertensive drug prescription patterns in Indian healthcare settings. An observational, cross‐sectional, prospective prescription registry analyzed prescriptions for 4723 newly diagnosed hypertension patients ...
Thomas Alexander   +24 more
doaj   +1 more source

Pharmacokinetics, Tolerability and Pharmacogenetics of DA-8031 After Multiple Ascending Doses in Healthy Male Subjects

open access: yesDrug Design, Development and Therapy, 2021
Sejung Hwang,1 Dae Young Lee,2 Joo-Youn Cho,1,3 Jae-Yong Chung,4 In-Jin Jang,1 Kyung-Sang Yu,1,3 SeungHwan Lee1 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea ...
Hwang S   +6 more
doaj  

Histone Deacetylase 6 Brain PET in Amyotrophic Lateral Sclerosis‐Frontotemporal Spectrum Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective [18F]EKZ‐001 is a positron emission tomography (PET) tracer targeting histone deacetylase 6 (HDAC6), an enzyme responsible for intracellular transport and clearance of misfolded proteins. HDAC6 modulation is a promising treatment strategy in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS).
Greet Vanderlinden   +15 more
wiley   +1 more source

Myostatin Levels in SMA Following Disease‐Modifying Treatments: A Multi‐Center Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study investigated myostatin levels in SMA patients receiving disease‐modifying therapies (DMTs) to understand their relationship with treatment duration and functional status. Methods Our study includes both cross‐sectional and longitudinal analyses of myostatin levels in treated SMA patients.
Fiorella Piemonte   +23 more
wiley   +1 more source

An account on the history of pharmacology in Spain

open access: yesPharmacological Research
Here we present an account on the history of pharmacology in Spain. Pharmacology as an independent science in Europe began with the creation of university chairs.
Ana María Aldea-Perona   +5 more
doaj  

'Seminar-CBL-Ideological and Political Education' Innovative Mode in Clinical Pharmacology Teaching

open access: yesXiehe Yixue Zazhi
Clinical pharmacology is an important discipline that bridges clinical medicine and pharmacology. In the teaching practice, it is necessary to keep up with educational reform and adopt the seminar teaching method combined with case-based learning (CBL ...
DU Ping, LIU He, AN Zhuoling
doaj   +1 more source

Comorbid anxiety predicts lower odds of depression improvement during smartphone-delivered psychotherapy [PDF]

open access: yesarXiv
Comorbid anxiety disorders are common among patients with major depressive disorder (MDD), and numerous studies have identified an association between comorbid anxiety and resistance to pharmacological depression treatment. However, the impact of anxiety on the effectiveness of non-pharmacological interventions for MDD is not as well understood.
arxiv  

New method for the study of psychotropic drug effects under simulated clinical conditions [PDF]

open access: yesarXiv, 2007
The sensory contact model allows forming different psychopathological states (anxious depression, catalepsy, social withdrawal, pathological aggression, hypersensitivity, cognition disturbances, anhedonia, alcoholism etc.) produced by repeated agonistic interactions in male mice and investigating the therapeutic and preventive properties of any drug as
arxiv  

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