Results 41 to 50 of about 9,870,305 (401)
Animals, 2023 This review firstly examines the underlying pathophysiology of pain and inflammation associated with orthopedic disease and endotoxemia. Then, it reviews the clinical pharmacology (pharmacokinetics and pharmacodynamics) of both conventional and non ...
Melissa A. Mercer +2 more
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Pharmacokinetics and Clinical Pharmacology of Monoclonal Antibodies in Pediatric Patients
Pediatric Drugs, 2020 Monoclonal antibodies (mAbs) and their derivatives are increasingly used in pediatric pharmacotherapy, and the number of antibody-based drug products with approved pediatric indications is continuously growing.
Zaid H. Temrikar +2 more
semanticscholar +1 more source
Pharmacogenetics : the science of predictive clinical pharmacology [PDF]
, 2014 The study of pharmacogenetics has expanded from what were initially casual family-based clinical drug response observations, to a fully-fledged science with direct therapeutic applications, all within a time-span of less than 60 years. A wide spectrum of
Fenech, Anthony G., Grech, Godfrey
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Effect of severe renal impairment on pharmacokinetics, safety, and tolerability of lemborexant
Pharmacology Research & Perspectives, 2021 The primary aim of this study was to examine the effect of severe renal impairment (SRI) on the pharmacokinetics of lemborexant, a dual orexin receptor antagonist indicated for the treatment of insomnia.
Ishani Landry +6 more
doaj +1 more source
Children, 2023 This was a single center, retrospective cohort study designed to evaluate the association between the administration of inotropes to hypotensive very low gestational age infants (VLGAI) and prenatal and neonatal risk factors.
Theodora Stathopoulou +5 more
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Integrating pharmacology and clinical pharmacology [PDF]
British Journal of Clinical Pharmacology, 2011 I here reaffirm some of the points that I made in the manifesto for UK clinical pharmacology [1], in response to letters from others. Much of what I wrote in the manifesto addresses points that correspondents have made, but as some of the important points may not have been clear on a first reading, I shall reiterate them and add clarifications. I am
openaire +3 more sources
Traditional Chinese Medicine and Clinical Pharmacology
Drug Discovery and Evaluation: Methods in Clinical Pharmacology, 2020 Traditional Chinese Medicine (TCM) represents thousands of years in treatment protocols for health, healing, and longevity and has evolved into a complex healthcare system.
A. Marshall
semanticscholar +1 more source
Pharmacy, 2021 Judicious use of medicines that considers evidence-based practice, together with cost-effectiveness, is a priority for all health care organisations. We describe an initiative to lead a Medication Utilisation Program, incorporating medication quality ...
Karen Whitfield +3 more
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Neonatal clinical pharmacology [PDF]
Pediatric Anesthesia, 2013 SummaryEffective and safe drug administration in neonates should be based on integrated knowledge on the evolving physiological characteristics of the infant who will receive the drug and the pharmacokinetics (PK) and pharmacodynamics (PD) of a given drug.
Karel Allegaert +4 more
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On the Clinical Pharmacology of Reactive Oxygen Species
Pharmacological Reviews, 2020 Reactive oxygen species (ROS) have been correlated with almost every human disease. Yet clinical exploitation of these hypotheses by pharmacological modulation of ROS has been scarce to nonexistent. Are ROS, thus, irrelevant for disease? No.
A. I. Casas +15 more
semanticscholar +1 more source