Results 21 to 30 of about 519,368 (313)

Clinical Pharmacology of Sisomicin [PDF]

Antimicrobial Agents and Chemotherapy, 1975
Studies were conducted in 30 patients with neoplastic diseases. Twelve patients received sisomicin intramuscularly at doses of 20 mg/m 2 and 40 mg/m 2 . The mean peak serum concentration occurred at 1 h and was 2.5 μg/ml and 4.0 μg/ml, respectively. Ten patients received intravenous sisomicin
V, Rodriguez, G P, Bodey, M, Valdivieso, R, Feld   +3 more
openaire   +2 more sources

Where are the Ambulatory Care Pediatric Pharmacists?

Children, 2019
This editorial describes the purposes and content of the Special Issue for the development of a national pediatric pharmacotherapy collaborative practice network.
Richard H. Parrish, Johannes van den Anker, Sandra Benavides   +2 more
doaj   +1 more source

Pharmaceutical development of an amorphous solid dispersion formulation of elacridar hydrochloride for proof-of-concept clinical studies [PDF]

, 2017
Objective: A novel tablet formulation containing an amorphous solid dispersion (ASD) of elacridar hydrochloride was developed with the purpose to resolve the drug’s low solubility in water and to conduct proof-of-concept clinical studies.
Schellens, J. H M, Nuijen, B., Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Beijnen, J. H., Sawicki, E.   +5 more
core   +1 more source

Will Artificial Intelligence for Drug Discovery Impact Clinical Pharmacology? [PDF]

, 2020
As the field of artificial intelligence and machine learning (AI/ML) for drug discovery is rapidly advancing, we address the question "What is the impact of recent AI/ML trends in the area of Clinical Pharmacology?" We address difficulties and AI/ML ...
Zhavoronkov, Alex, Alex Zhavoronkov, Oprea, Tudor I., Zhavoronkov, A., Quentin Vanhaelen, Tudor I. Oprea, Vanhaelen, Quentin, Vanhaelen, Q., Oprea, Tudor I,   +8 more
core   +1 more source

The prescription talk – an approach to teach patient-physician conversation about drug prescription to medical students

GMS Journal for Medical Education, 2017
Background: Medication communication from physicians to patients often is poor, by this among others enhancing the risk of non-adherence. In this context, a neglect regarding the prescription talk has been complained.Aim of the project: In a newly ...
Hauser, Katarina, Koerfer, Armin, Niehaus, Mathilde, Albus, Christian, Herzig, Stefan, Matthes, Jan   +5 more
doaj   +1 more source

Clinical pharmacology of cefazolin

Advances in Biomedical and Health Sciences, 2022
Cefazolin is a first-generation cephalosporin that is active against gram-positive bacteria and has modest activity against gram-negative organisms, and cefazolin is excreted by glomerular filtration.
Gian Maria Pacifici
doaj   +1 more source

Safe use of meloxicam in clinical practice

Медицинский совет, 2019
Non-steroidal anti-inflammatory drugs (NSAIDs) – means of treatment of acute and chronic pain associated primarily with inflammatory changes, so this group of drugs is widely used in neurology, rheumatology, traumatology, etc.
E. I. Sas, V. B. Grinevich
doaj   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source