Will Artificial Intelligence for Drug Discovery Impact Clinical Pharmacology?
Clinical pharmacology and therapy, 2020 As the field of artificial intelligence and machine learning (AI/ML) for drug discovery is rapidly advancing, we address the question “What is the impact of recent AI/ML trends in the area of Clinical Pharmacology?” We address difficulties and AI/ML ...
A. Zhavoronkov +2 more
semanticscholar +1 more source
Clinical Pharmacology and Interplay of Immune Checkpoint Agents: A Yin-Yang Balance.
Annual Review of Pharmacology and Toxicology, 2020 T cells have a central role in immune system balance. When activated, they may lead to autoimmune diseases. When too anergic, they contribute to infection spread and cancer proliferation.
A. Géraud +9 more
semanticscholar +1 more source
Effectiveness of Revised Pharmacology Record Books as a Teaching-Learning Method for Second Year Medical Students [PDF]
Journal of Clinical and Diagnostic Research, 2016 Introduction: The goal of teaching medical undergraduates Pharmacology is to form a sound foundation of therapeutics. The pharmacology record books are maintained as a part of the curriculum.
Dhanya Sasidharan Palappallil +1 more
doaj +1 more source
Pharmacology and clinical drug candidates in redox medicine [PDF]
, 2015 SIGNIFICANCE Oxidative stress is suggested to be a disease mechanism common to a wide range of disorders affecting human health. However, so far, the pharmacotherapeutic exploitation of this, for example, based on chemical scavenging of pro-oxidant ...
Casas, Ana I +11 more
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Pharmacokinetics and Clinical Pharmacology of Monoclonal Antibodies in Pediatric Patients
Pediatric Drugs, 2020 Monoclonal antibodies (mAbs) and their derivatives are increasingly used in pediatric pharmacotherapy, and the number of antibody-based drug products with approved pediatric indications is continuously growing.
Zaid H. Temrikar +2 more
semanticscholar +1 more source
Effect of severe renal impairment on pharmacokinetics, safety, and tolerability of lemborexant
Pharmacology Research & Perspectives, 2021 The primary aim of this study was to examine the effect of severe renal impairment (SRI) on the pharmacokinetics of lemborexant, a dual orexin receptor antagonist indicated for the treatment of insomnia.
Ishani Landry +6 more
doaj +1 more source
Toward a clinical practice guide in pharmacogenomics testing for functional polymorphisms of drug-metabolizing enzymes. Gene/drug pairs and barriers perceived in Spain [PDF]
, 2012 The development of clinica lpractice recommendations or guidelines for the clinical use of biomarkers is an issue of great importance withr regard to adverse drug reactions.The poten-tial of pharmacogenomicbiomarkers has been extensively investigated in
Abad Santos, Francisco +18 more
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Traditional Chinese Medicine and Clinical Pharmacology
Drug Discovery and Evaluation: Methods in Clinical Pharmacology, 2020 Traditional Chinese Medicine (TCM) represents thousands of years in treatment protocols for health, healing, and longevity and has evolved into a complex healthcare system.
A. Marshall
semanticscholar +1 more source
DeckerMed Surgery, 2020 Critically ill patients often require surgical procedures and therapeutic interventions that produce significant pathophysiologic changes. Drug pharmacology can be greatly altered in this population wherein comorbid diseases, varied organ function, and polypharmacy can produce adverse drug reactions (ADRs).
Eric W. Mueller, Molly Droege
openaire +2 more sources
Effects of Clinical Pharmacology Training on Prescription Writing Skills of Interns [PDF]
, 2013 Introduction: The skill of appropriate prescription writing is a corner stone of treatment. Due to this fact, we designed a study for evaluating interns prescription writing skills after clinical pharmacology training.
Hamid Noshad, Parviz Saleh
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