Results 11 to 20 of about 11,531,725 (348)

International Union of Basic and Clinical Pharmacology. CXII: Adenosine Receptors: A Further Update

open access: yesPharmacological Reviews, 2022
Our previous International Union of Basic and Clinical Pharmacology report on the nomenclature and classification of adenosine receptors (2011) contained a number of emerging developments with respect to this G protein-coupled receptor subfamily ...
A. IJzerman   +4 more
semanticscholar   +1 more source

Clinical Pharmacokinetics of Oral Semaglutide: Analyses of Data from Clinical Pharmacology Trials

open access: yesClinical Pharmacokinetics, 2021
The absorption, distribution and elimination of oral semaglutide, the first oral glucagon-like peptide-1 receptor agonist for treating type 2 diabetes, was investigated using a population pharmacokinetic model based on data from clinical pharmacology ...
R. V. Overgaard   +4 more
semanticscholar   +1 more source

Clinical Pharmacology of RNA Interference–Based Therapeutics: A Summary Based on Food and Drug Administration–Approved Small Interfering RNAs

open access: yesDrug Metabolism And Disposition, 2022
RNA-based oligonucleotide therapeutics are revolutionizing drug development for disease treatment. This class of therapeutics differs from small molecules and protein therapeutics in various ways, including both its mechanism of action and clinical ...
Xing Jing   +3 more
semanticscholar   +1 more source

Clinical Pharmacology of Antibody-Drug Conjugates

open access: yesAntibodies, 2021
Antibody-drug conjugates (ADCs) are biopharmaceutical products where a monoclonal antibody is linked to a biologically active drug (a small molecule) forming a conjugate.
I. Mahmood
semanticscholar   +1 more source

Filgotinib: A Clinical Pharmacology Review

open access: yesClinical Pharmacokinetics, 2022
Filgotinib (GS-6034, formerly GLPG0634; Jyseleca®) is an oral, preferential Janus kinase (JAK)-1 inhibitor. Preferential inhibition of JAK1 modulates a subset of proinflammatory cytokines within the JAK–signal transducer and activator of transcription ...
F. Namour   +3 more
semanticscholar   +1 more source

Sex and Gender Differences in Clinical Pharmacology: Implications for Transgender Medicine

open access: yesClinical pharmacology and therapy, 2021
The transgender adult population is growing globally, but clinical pharmacology has lagged behind other areas of transgender medicine. Medical care for transgender adults may include long‐term testosterone or estrogen treatment to align secondary sex ...
Lauren R. Cirrincione, Kai J. Huang
semanticscholar   +1 more source

Prescriptive Appropriateness: Inhospital Adherence to Proton Pump Inhibitors Deprescription Flow Chart

open access: yesPharmaceuticals, 2023
The prescriptive appropriateness of Proton Pump Inhibitors (PPIs) in polypharmacy is controversial. PPIs are often overprescribed and the risk of prescribing errors and adverse drug reactions increases for each additional drug added to therapy.
Giammarco Baiardi   +7 more
doaj   +1 more source

Basic & Clinical Pharmacology 14th Edition

open access: yesCentral Asian Journal of Medical Sciences, 2020
No abstract  in ...
Narantungalag Dorjsuren
doaj   +1 more source

Strong Association between Inotrope Administration and Intraventricular Hemorrhage, Gestational Age, and the Use of Fentanyl in Very Low Gestational Age Infants: A Retrospective Study

open access: yesChildren, 2023
This was a single center, retrospective cohort study designed to evaluate the association between the administration of inotropes to hypotensive very low gestational age infants (VLGAI) and prenatal and neonatal risk factors.
Theodora Stathopoulou   +5 more
doaj   +1 more source

Medication Utilisation Program, Quality Improvement and Research Pharmacist—Implementation Strategies and Preliminary Findings

open access: yesPharmacy, 2021
Judicious use of medicines that considers evidence-based practice, together with cost-effectiveness, is a priority for all health care organisations. We describe an initiative to lead a Medication Utilisation Program, incorporating medication quality ...
Karen Whitfield   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy